# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4872902 | d12 | t1/2 | = | 2.33 | hr | ALA4808884 | hr | ||||
2. | ALA4872902 | d12 | Activity | 0 | ALA4808883 | Non-Toxic | ||||||
3. | ALA4872902 | d12 | Activity | 0 | ALA4808882 | Non-Toxic | ||||||
4. | ALA4872902 | d12 | Activity | 0 | ALA4808881 | Non-Toxic | ||||||
5. | ALA4872902 | d12 | Activity | 0 | ALA4808880 | Non-Toxic | ||||||
6. | ALA4872902 | d12 | Activity | 0 | ALA4808879 | Non-Toxic | ||||||
7. | ALA4872902 | d12 | Activity | < | 5 | % | ALA4808878 | % | ||||
8. | ALA4872902 | d12 | Activity | 0 | ALA4808877 | Non-Toxic | ||||||
9. | ALA4872902 | d12 | CL | = | 185.6 | ml/hr | ALA4808876 | ml/hr | ||||
10. | ALA4872902 | d12 | Vd | = | 625 | ml | ALA4808875 | ml | ||||
11. | ALA4872902 | d12 | AUC | = | 16162.1 | ng/mL.hr | ALA4808874 | ng.hr.mL-1 | ||||
12. | ALA4872902 | d12 | AUC | = | 14057.5 | ng/mL.hr | ALA4808873 | ng.hr.mL-1 | ||||
13. | ALA4872902 | d12 | Cmax | = | 3995 | ng/ml | ALA4808872 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
14. | ALA4872902 | d12 | Tmax | = | 2 | hr | ALA4808871 | hr | ||||
15. | ALA4872902 | d12 | Kel | = | 0.3 | /hr | ALA4808870 | /hr | ||||
16. | ALA4872902 | d12 | PPB | = | 13 | % | ALA4808869 | % | ||||
17. | ALA4872902 | d12 | CLH | = | 320.4 | ml/min.kg | ALA4808868 | mL.min-1.kg-1 | ||||
18. | ALA4872902 | d12 | t1/2 | = | 22 | hr | ALA4808867 | hr | ||||
19. | ALA4872902 | d12 | EC50 | = | 6.7 | uM | ALA4808866 | 5.17 | nM | Homo sapiens | ||
20. | ALA4872902 | d12 | INH | 0 | ALA4808865 | Active | % | Homo sapiens |