# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4872965 | 45 | Drug uptake | = | 116 | ng/g | ALA4844626 | ng/g | ||||
2. | ALA4872965 | 45 | Drug uptake | = | 129 | ng/g | ALA4844625 | ng/g | ||||
3. | ALA4872965 | 45 | Drug uptake | = | 123 | ng/g | ALA4844624 | ng/g | ||||
4. | ALA4872965 | 45 | Drug uptake | = | 108 | ng/g | ALA4844623 | ng/g | ||||
5. | ALA4872965 | 45 | Cp | = | 106 | ng/ml | ALA4844622 | ng/ml | ||||
6. | ALA4872965 | 45 | Cp | = | 181 | ng/ml | ALA4844621 | ng/ml | ||||
7. | ALA4872965 | 45 | INH | 0 | ALA4844620 | Active | % | Homo sapiens | ||||
8. | ALA4872965 | 45 | INH | > | 90 | % | ALA4844619 | % | Homo sapiens | |||
9. | ALA4872965 | 45 | INH | > | 90 | % | ALA4844618 | % | Homo sapiens | |||
10. | ALA4872965 | 45 | INH | > | 90 | % | ALA4844617 | % | Homo sapiens | |||
11. | ALA4872965 | 45 | INH | > | 90 | % | ALA4844616 | % | Homo sapiens | |||
12. | ALA4872965 | 45 | IC50 | = | 21.7 | nM | ALA4844615 | 7.66 | nM | Homo sapiens | ||
13. | ALA4872965 | 45 | Emax | = | 64 | % | ALA4844614 | % | Homo sapiens | |||
14. | ALA4872965 | 45 | DC50 | = | 1.3 | nM | ALA4844613 | nM | Homo sapiens | |||
15. | ALA4872965 | 45 | IC50 | = | 5.1 | nM | ALA4844612 | 8.29 | nM | Homo sapiens | ||
16. | ALA4872965 | 45 | F | = | 67 | % | ALA4844606 | % | ||||
17. | ALA4872965 | 45 | AUCt | = | 8637 | hr.ng/ml | ALA4844605 | ng.hr.mL-1 | ||||
18. | ALA4872965 | 45 | Cmax | = | 484 | ng/ml | ALA4844604 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
19. | ALA4872965 | 45 | t1/2 | = | 26.8 | hr | ALA4844603 | hr | ||||
20. | ALA4872965 | 45 | Tmax | = | 4.7 | hr | ALA4844602 | hr |