# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4873182 | 32 | t1/2 | = | 0.4 | hr | ALA4809949 | hr | ||||
2. | ALA4873182 | 32 | t1/2 | = | 0.4 | hr | ALA4809948 | hr | ||||
3. | ALA4873182 | 32 | CL free | = | 171 | ml/min.kg | ALA4809947 | mL.min-1.kg-1 | ||||
4. | ALA4873182 | 32 | CL free | = | 147 | ml/min.kg | ALA4809946 | mL.min-1.kg-1 | ||||
5. | ALA4873182 | 32 | Fu | = | 0.258 | ALA4809924 | ||||||
6. | ALA4873182 | 32 | Fu | = | 0.161 | ALA4809923 | ||||||
7. | ALA4873182 | 32 | Fu | = | 0.354 | ALA4809922 | ||||||
8. | ALA4873182 | 32 | F | = | 14 | % | ALA4809921 | % | ||||
9. | ALA4873182 | 32 | F | = | 39 | % | ALA4809920 | % | ||||
10. | ALA4873182 | 32 | Vdss | = | 1.3 | L/Kg | ALA4809919 | L.kg-1 | ||||
11. | ALA4873182 | 32 | Vdss | = | 1.7 | L/Kg | ALA4809918 | L.kg-1 | ||||
12. | ALA4873182 | 32 | CL | = | 44 | ml/min.kg | ALA4809917 | mL.min-1.kg-1 | ||||
13. | ALA4873182 | 32 | CL | = | 52 | ml/min.kg | ALA4809916 | mL.min-1.kg-1 | ||||
14. | ALA4873182 | 32 | CLH | < | 0.45 | ml/min/g | ALA4809915 | mL.min-1.g-1 | ||||
15. | ALA4873182 | 32 | CLH | < | 0.65 | ml/min/g | ALA4809914 | mL.min-1.g-1 | ||||
16. | ALA4873182 | 32 | CLH | = | 2.03 | ml/min/g | ALA4809913 | mL.min-1.g-1 | ||||
17. | ALA4873182 | 32 | pIC50 | = | 7 | ALA4809912 | 7.00 | nM | Homo sapiens | |||
18. | ALA4873182 | 32 | permeability | = | 370 | nm/s | ALA4809911 | nm/s | ||||
19. | ALA4873182 | 32 | solubility | = | 117 | ug ml-1 | ALA4809910 | ug.mL-1 | ||||
20. | ALA4873182 | 32 | logD | = | 4.1 | ALA4809909 |