# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4873385 | 20b | Cmax | = | 1300 | ng/ml | ALA4836340 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
2. | ALA4873385 | 20b | beta t1/2 | = | 2.1 | hr | ALA4836339 | hr | ||||
3. | ALA4873385 | 20b | AUC/dose | = | 2200 | ng.hr/ml | ALA4836338 | ng.hr/ml | ||||
4. | ALA4873385 | 20b | solubility | = | 0.002 | mg/ml | ALA4836337 | ug.mL-1 | ||||
5. | ALA4873385 | 20b | IC50 | = | 18 | nM | ALA4836336 | 7.75 | nM | Homo sapiens | ||
6. | ALA4873385 | 20b | t1/2 | > | 180 | min | ALA4836335 | hr | ||||
7. | ALA4873385 | 20b | IC50 | = | 160 | nM | ALA4836334 | 6.80 | nM | Rattus norvegicus |