| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4873528 | 22 | EC50 | = | 1.6 | nM | ALA4825945 | 8.80 | nM | Human orthopneumovirus | ||
| 2. | ALA4873528 | 22 | F | = | 4.4 | % | ALA4825942 | % | ||||
| 3. | ALA4873528 | 22 | Cmax | = | 47.8 | ng/ml | ALA4825937 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 4. | ALA4873528 | 22 | Tmax | = | 0.1 | hr | ALA4825932 | hr | ||||
| 5. | ALA4873528 | 22 | t1/2 | = | 0.9 | hr | ALA4825928 | hr | ||||
| 6. | ALA4873528 | 22 | t1/2 | 0 | ALA4825926 | Not Determined | ||||||
| 7. | ALA4873528 | 22 | CC50 | > | 25000 | nM | ALA4825923 | nM | Homo sapiens | |||
| 8. | ALA4873528 | 22 | CLH | 0 | ALA4825918 | Not Determined | ||||||
| 9. | ALA4873528 | 22 | CLH | 0 | ALA4825917 | Not Determined | ||||||
| 10. | ALA4873528 | 22 | CLH | 0 | ALA4825916 | Not Determined | ||||||
| 11. | ALA4873528 | 22 | F | = | 4.4 | % | ALA4825915 | % | ||||
| 12. | ALA4873528 | 22 | Ratio | = | 21 | ALA4825910 | ||||||
| 13. | ALA4873528 | 22 | Papp | = | 2.8 | 10^-6 cm/s | ALA4825909 | 10^-6 cm/s | ||||
| 14. | ALA4873528 | 22 | Papp | = | 0.1 | 10^-6 cm/s | ALA4825908 | 10^-6 cm/s | ||||
| 15. | ALA4873528 | 22 | Therm_solubility | = | 313 | uM | ALA4825907 | nM | ||||
| 16. | ALA4873528 | 22 | IC50 | = | 2.6 | nM | ALA4825906 | 8.59 | nM | Human respiratory syncytial virus A (strain A2) | ||
| 17. | ALA4873528 | 22 | Vdss | = | 3.8 | L/Kg | ALA4825902 | L.kg-1 | ||||
| 18. | ALA4873528 | 22 | CL | = | 82.7 | ml/min.kg | ALA4825901 | mL.min-1.kg-1 | ||||
| 19. | ALA4873528 | 22 | t1/2 | = | 300 | min | ALA4825899 | hr | ||||
| 20. | ALA4873528 | 22 | t1/2 | = | 147 | min | ALA4825898 | hr |
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