| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4873642 | 3r | F | = | 100 | % | ALA4835470 | % | ||||
| 2. | ALA4873642 | 3r | t1/2 | = | 1.8 | hr | ALA4835469 | hr | ||||
| 3. | ALA4873642 | 3r | Vdu | = | 1.9 | L/Kg | ALA4835468 | L.kg-1 | ||||
| 4. | ALA4873642 | 3r | Vd | = | 1.7 | L/Kg | ALA4835467 | L.kg-1 | ||||
| 5. | ALA4873642 | 3r | CL | = | 16 | ml/min.kg | ALA4835466 | mL.min-1.kg-1 | ||||
| 6. | ALA4873642 | 3r | CL | = | 9.3 | ml/min.kg | ALA4835465 | mL.min-1.kg-1 | ||||
| 7. | ALA4873642 | 3r | F | = | 50 | % | ALA4835462 | % | ||||
| 8. | ALA4873642 | 3r | t1/2 | = | 1.7 | hr | ALA4835461 | hr | ||||
| 9. | ALA4873642 | 3r | Vdu | = | 3.2 | L/Kg | ALA4835460 | L.kg-1 | ||||
| 10. | ALA4873642 | 3r | Vd | = | 0.5 | L/Kg | ALA4835459 | L.kg-1 | ||||
| 11. | ALA4873642 | 3r | CL | = | 25 | ml/min.kg | ALA4835458 | mL.min-1.kg-1 | ||||
| 12. | ALA4873642 | 3r | CL | = | 3.7 | ml/min.kg | ALA4835457 | mL.min-1.kg-1 | ||||
| 13. | ALA4873642 | 3r | logD | = | 0.7 | ALA4835456 | ||||||
| 14. | ALA4873642 | 3r | IC50 | = | 600 | nM | ALA4835454 | 6.22 | nM | Homo sapiens | ||
| 15. | ALA4873642 | 3r | IC50 | > | 10 | uM | ALA4835453 | nM | ||||
| 16. | ALA4873642 | 3r | IC50 | = | 94 | nM | ALA4835452 | 7.03 | nM | Homo sapiens | ||
| 17. | ALA4873642 | 3r | Ratio IC50 | = | 140 | ALA4835451 | ||||||
| 18. | ALA4873642 | 3r | IC50 | = | 6.4 | nM | ALA4835450 | 8.19 | nM | Homo sapiens |
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