# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4873843 | 3f | CL | = | 270 | ml/min.kg | ALA4835523 | mL.min-1.kg-1 | ||||
2. | ALA4873843 | 3f | CL | = | 28 | ml/min.kg | ALA4835522 | mL.min-1.kg-1 | ||||
3. | ALA4873843 | 3f | t1/2 | = | 1.1 | hr | ALA4835469 | hr | ||||
4. | ALA4873843 | 3f | Vdu | = | 1.4 | L/Kg | ALA4835468 | L.kg-1 | ||||
5. | ALA4873843 | 3f | Vd | = | 1 | L/Kg | ALA4835467 | L.kg-1 | ||||
6. | ALA4873843 | 3f | CL | = | 27 | ml/min.kg | ALA4835464 | mL.min-1.kg-1 | ||||
7. | ALA4873843 | 3f | CL | = | 12 | ml/min.kg | ALA4835463 | mL.min-1.kg-1 | ||||
8. | ALA4873843 | 3f | t1/2 | = | 0.3 | hr | ALA4835461 | hr | ||||
9. | ALA4873843 | 3f | Vdu | = | 4 | L/Kg | ALA4835460 | L.kg-1 | ||||
10. | ALA4873843 | 3f | Vd | = | 0.6 | L/Kg | ALA4835459 | L.kg-1 | ||||
11. | ALA4873843 | 3f | logD | = | 1.3 | ALA4835456 | ||||||
12. | ALA4873843 | 3f | IC50 | = | 7.7 | uM | ALA4835453 | 5.11 | nM | |||
13. | ALA4873843 | 3f | IC50 | = | 14 | nM | ALA4835452 | 7.85 | nM | Homo sapiens | ||
14. | ALA4873843 | 3f | Ratio IC50 | = | 530 | ALA4835451 | ||||||
15. | ALA4873843 | 3f | IC50 | = | 1.2 | nM | ALA4835450 | 8.92 | nM | Homo sapiens |