# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4873922 | 23j | IC50 | = | 0.3 | ug ml-1 | ALA4831718 | ug.mL-1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
2. | ALA4873922 | 23j | Ratio | > | 4 | ALA4831717 | ||||||
3. | ALA4873922 | 23j | MIC | = | 0.32 | ug ml-1 | ALA4831716 | ug.mL-1 | Mycobacterium tuberculosis | |||
4. | ALA4873922 | 23j | MIC | = | 0.32 | ug ml-1 | ALA4831715 | ug.mL-1 | Mycobacterium tuberculosis | |||
5. | ALA4873922 | 23j | MIC | > | 1.28 | ug ml-1 | ALA4831714 | ug.mL-1 | Mycobacterium tuberculosis | |||
6. | ALA4873922 | 23j | IC50 | = | 23.7 | ug ml-1 | ALA4831696 | ug.mL-1 | Homo sapiens | |||
7. | ALA4873922 | 23j | IC50 | > | 64 | ug ml-1 | ALA4831695 | ug.mL-1 | Homo sapiens | |||
8. | ALA4873922 | 23j | Stability | = | 66.4 | % | ALA4831694 | % | ||||
9. | ALA4873922 | 23j | t1/2 | = | 50.8 | min | ALA4831693 | hr | ||||
10. | ALA4873922 | 23j | Stability | = | 69.1 | % | ALA4831692 | % | ||||
11. | ALA4873922 | 23j | t1/2 | = | 56.4 | min | ALA4831691 | hr | ||||
12. | ALA4873922 | 23j | Activity | = | 0.98 | deltalog10CFU | ALA4831690 | deltalog10CFU | Mycobacterium tuberculosis | |||
13. | ALA4873922 | 23j | Activity | = | 4.54 | log10CFU | ALA4831689 | log10CFU | Mycobacterium tuberculosis | |||
14. | ALA4873922 | 23j | Activity | = | 1.07 | deltalog10CFU | ALA4831688 | deltalog10CFU | Mycobacterium tuberculosis | |||
15. | ALA4873922 | 23j | Activity | = | 4.45 | log10CFU | ALA4831687 | log10CFU | Mycobacterium tuberculosis | |||
16. | ALA4873922 | 23j | MIC | = | 0.14 | ug ml-1 | ALA4831685 | ug.mL-1 | ||||
17. | ALA4873922 | 23j | MIC | = | 0.059 | ug ml-1 | ALA4831684 | ug.mL-1 | ||||
18. | ALA4873922 | 23j | MIC | = | 0.082 | ug ml-1 | ALA4831683 | ug.mL-1 | ||||
19. | ALA4873922 | 23j | MIC | = | 0.055 | ug ml-1 | ALA4831682 | ug.mL-1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |||
20. | ALA4873922 | 23j | Selectivity Index | > | 3200 | ALA4831681 |