# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4874034 | 54 | Ratio IC50 | = | 5.1 | ALA4835260 | ||||||
2. | ALA4874034 | 54 | IC50 | = | 1.5 | uM | ALA4835259 | 5.82 | nM | Homo sapiens | ||
3. | ALA4874034 | 54 | IC50 | = | 7.8 | uM | ALA4835258 | 5.11 | nM | Homo sapiens | ||
4. | ALA4874034 | 54 | CL | < | 1.95 | L/hr.Kg | ALA4835254 | mL.min-1.kg-1 | ||||
5. | ALA4874034 | 54 | Papp | = | 9.7 | 10^-6 cm/s | ALA4835226 | 10^-6 cm/s | ||||
6. | ALA4874034 | 54 | INH | = | 76 | % | ALA4835210 | % | Mus musculus | |||
7. | ALA4874034 | 54 | PPB | = | 67 | % | ALA4835209 | % | ||||
8. | ALA4874034 | 54 | INH | 0 | ALA4835203 | Not Active | % | Homo sapiens | ||||
9. | ALA4874034 | 54 | PPB | = | 82 | % | ALA4835199 | % | ||||
10. | ALA4874034 | 54 | INH | < | 50 | % | ALA4835198 | % | Homo sapiens | |||
11. | ALA4874034 | 54 | INH | < | 65 | % | ALA4835197 | % | Homo sapiens | |||
12. | ALA4874034 | 54 | INH | < | 50 | % | ALA4835196 | % | Homo sapiens | |||
13. | ALA4874034 | 54 | INH | < | 50 | % | ALA4835195 | % | Homo sapiens | |||
14. | ALA4874034 | 54 | INH | < | 50 | % | ALA4835194 | % | Homo sapiens | |||
15. | ALA4874034 | 54 | INH | < | 50 | % | ALA4835193 | % | Homo sapiens | |||
16. | ALA4874034 | 54 | CLH | = | 3.62 | L/hr/kg | ALA4835192 | mL.min-1.kg-1 | ||||
17. | ALA4874034 | 54 | CLH | = | 1.85 | L/hr/kg | ALA4835191 | mL.min-1.kg-1 | ||||
18. | ALA4874034 | 54 | IC50 | = | 18 | nM | ALA4835175 | 7.75 | nM | Homo sapiens | ||
19. | ALA4874034 | 54 | IC50 | = | 5 | nM | ALA4835173 | 8.30 | nM | |||
20. | ALA4874034 | 54 | IC50 | = | 12 | nM | ALA4835172 | 7.92 | nM | Homo sapiens |