| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4874648 | 11 | Activity | 0 | ALA4834339 | Non-Toxic | ||||||
| 2. | ALA4874648 | 11 | Activity | 0 | ALA4834332 | Active | Mus musculus | |||||
| 3. | ALA4874648 | 11 | fCmax | = | 0.26 | uM | ALA4834330 | uM | ||||
| 4. | ALA4874648 | 11 | fAUC | = | 1.6 | uM.hr | ALA4834327 | uM.hr | ||||
| 5. | ALA4874648 | 11 | Cmax | = | 8.3 | uM | ALA4834324 | nM | ||||
| 6. | ALA4874648 | 11 | AUC | = | 50 | uM.hr | ALA4834321 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 7. | ALA4874648 | 11 | PPB | = | 96.9 | % | ALA4834319 | % | ||||
| 8. | ALA4874648 | 11 | IC50 | = | 5.3 | uM | ALA4834318 | 5.28 | nM | Homo sapiens | ||
| 9. | ALA4874648 | 11 | IC50 | = | 25 | uM | ALA4834317 | 4.60 | nM | Homo sapiens | ||
| 10. | ALA4874648 | 11 | IC50 | = | 0.035 | uM | ALA4834316 | 7.46 | nM | Homo sapiens | ||
| 11. | ALA4874648 | 11 | Ratio | = | 0.02 | ALA4834315 | ||||||
| 12. | ALA4874648 | 11 | Ratio | = | 0.03 | ALA4834314 | ||||||
| 13. | ALA4874648 | 11 | F | = | 60 | % | ALA4834313 | % | ||||
| 14. | ALA4874648 | 11 | Cmax | = | 10 | uM | ALA4834311 | nM | ||||
| 15. | ALA4874648 | 11 | Cmax | = | 14 | uM | ALA4834310 | nM | ||||
| 16. | ALA4874648 | 11 | AUC | = | 120 | uM.hr | ALA4834307 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 17. | ALA4874648 | 11 | AUC | = | 41 | uM.hr | ALA4834306 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 18. | ALA4874648 | 11 | t1/2 | = | 3.7 | hr | ALA4834303 | hr | ||||
| 19. | ALA4874648 | 11 | t1/2 | = | 3 | hr | ALA4834302 | hr | ||||
| 20. | ALA4874648 | 11 | Vdss | = | 0.37 | L/Kg | ALA4834299 | L.kg-1 |
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