# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4874774 | 37 | logD | = | 170 | ALA4808444 | ||||||
2. | ALA4874774 | 37 | solubility | = | 21 | uM | ALA4808443 | nM | ||||
3. | ALA4874774 | 37 | solubility | = | 186 | uM | ALA4808442 | nM | ||||
4. | ALA4874774 | 37 | F | = | 46 | % | ALA4808441 | % | ||||
5. | ALA4874774 | 37 | MRT | = | 1.1 | hr | ALA4808440 | hr | ||||
6. | ALA4874774 | 37 | Vdu | = | 148 | L/Kg | ALA4808439 | L.kg-1 | ||||
7. | ALA4874774 | 37 | CL free | = | 2163 | ml/min.kg | ALA4808438 | mL.min-1.kg-1 | ||||
8. | ALA4874774 | 37 | CL | = | 27 | ml/min.kg | ALA4808437 | mL.min-1.kg-1 | ||||
9. | ALA4874774 | 37 | EC50 | = | 1.4 | nM | ALA4808436 | 8.85 | nM | Homo sapiens | ||
10. | ALA4874774 | 37 | EC50 | < | 0.5 | nM | ALA4808435 | nM | Homo sapiens |