# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4874957 | 4b | CL | = | 240 | ml/min.kg | ALA4835523 | mL.min-1.kg-1 | ||||
2. | ALA4874957 | 4b | CL | = | 15 | ml/min.kg | ALA4835522 | mL.min-1.kg-1 | ||||
3. | ALA4874957 | 4b | t1/2 | = | 0.7 | hr | ALA4835461 | hr | ||||
4. | ALA4874957 | 4b | Vdu | = | 8.3 | L/Kg | ALA4835460 | L.kg-1 | ||||
5. | ALA4874957 | 4b | Vd | = | 0.7 | L/Kg | ALA4835459 | L.kg-1 | ||||
6. | ALA4874957 | 4b | logD | = | 2.3 | ALA4835456 | ||||||
7. | ALA4874957 | 4b | IC50 | = | 5.6 | uM | ALA4835453 | 5.25 | nM | |||
8. | ALA4874957 | 4b | IC50 | = | 49 | nM | ALA4835452 | 7.31 | nM | Homo sapiens | ||
9. | ALA4874957 | 4b | Ratio IC50 | = | 72 | ALA4835451 | ||||||
10. | ALA4874957 | 4b | IC50 | = | 5.1 | nM | ALA4835450 | 8.29 | nM | Homo sapiens |