# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4875531 | 37 | CL | = | 37 | ml/min.kg | ALA4838714 | mL.min-1.kg-1 | ||||
2. | ALA4875531 | 37 | Vdss | = | 0.91 | L/Kg | ALA4838713 | L.kg-1 | ||||
3. | ALA4875531 | 37 | AUClast | = | 2.2 | uM.hr | ALA4838712 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
4. | ALA4875531 | 37 | Cmax | = | 6.7 | uM | ALA4838711 | nM | ||||
5. | ALA4875531 | 37 | t1/2 | = | 0.76 | hr | ALA4838710 | hr | ||||
6. | ALA4875531 | 37 | Ratio IC50 | = | 220 | ALA4838707 | ||||||
7. | ALA4875531 | 37 | Ratio IC50 | = | 1090 | ALA4838706 | ||||||
8. | ALA4875531 | 37 | IC50 | = | 4920 | nM | ALA4838705 | 5.31 | nM | Homo sapiens | ||
9. | ALA4875531 | 37 | IC50 | = | 100 | nM | ALA4838704 | 7.00 | nM | Homo sapiens | ||
10. | ALA4875531 | 37 | IC50 | = | 990 | nM | ALA4838703 | 6.00 | nM | Homo sapiens | ||
11. | ALA4875531 | 37 | IC50 | = | 4.5 | nM | ALA4838702 | 8.35 | nM | Homo sapiens |