Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA4876228	17; 17A	pIC50	=	8.1		ALA4832951	8.10	nM	Homo sapiens
2.	ALA4876228	17; 17A	pIC50	=	7.4		ALA4832950	7.40	nM	Homo sapiens
3.	ALA4876228	17; 17A	pIC50	=	5.8		ALA4832949	5.80	nM
4.	ALA4876228	17; 17A	pIC50	=	7.9		ALA4832944	7.90	nM	Homo sapiens
5.	ALA4876228	17; 17A	t1/2	>	1000	hr	ALA4832943		hr
6.	ALA4876228	17; 17A	t1/2	>	1000	hr	ALA4832942		hr
7.	ALA4876228	17; 17A	Activity	=	100	%	ALA4832941		%
8.	ALA4876228	17; 17A	Activity	>	70	%	ALA4832940		%
9.	ALA4876228	17; 17A	t1/2	=	24	hr	ALA4832936		hr
10.	ALA4876228	17; 17A	Vdss	=	14	L/Kg	ALA4832935		L.kg-1
11.	ALA4876228	17; 17A	CL	=	17	ml/min.kg	ALA4832934		mL.min-1.kg-1
12.	ALA4876228	17; 17A	CLH	=	0.72	ml/min/g	ALA4832933		mL.min-1.g-1
13.	ALA4876228	17; 17A	CLH	=	0.68	ml/min/g	ALA4832932		mL.min-1.g-1
14.	ALA4876228	17; 17A	logD	=	0.72		ALA4832931
15.	ALA4876228	17; 17A	solubility	=	180	uM	ALA4832930		nM
16.	ALA4876228	17; 17A	pIC50	=	8.8		ALA4832929	8.80	nM	Homo sapiens