| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4876457 | 98; DSM846 | Activity | 0 | ALA4812789 | Active | Plasmodium falciparum | |||||
| 2. | ALA4876457 | 98; DSM846 | fAUC | < | 0.47 | uM.hr | ALA4812784 | uM.hr | ||||
| 3. | ALA4876457 | 98; DSM846 | AUCED90 | < | 16 | uM.hr | ALA4812783 | uM.hr | Plasmodium falciparum | |||
| 4. | ALA4876457 | 98; DSM846 | ED50 | < | 20 | uM | ALA4812782 | uM | Plasmodium falciparum | |||
| 5. | ALA4876457 | 98; DSM846 | EC50 | = | 0.044 | uM | ALA4812781 | 7.36 | nM | Plasmodium vivax | ||
| 6. | ALA4876457 | 98; DSM846 | EC50 | = | 0.06 | uM | ALA4812780 | 7.22 | nM | Plasmodium falciparum | ||
| 7. | ALA4876457 | 98; DSM846 | EC50 | = | 0.02 | uM | ALA4812778 | 7.70 | nM | Plasmodium falciparum | ||
| 8. | ALA4876457 | 98; DSM846 | EC50 | = | 0.008 | uM | ALA4812777 | 8.10 | nM | Plasmodium falciparum | ||
| 9. | ALA4876457 | 98; DSM846 | EC50 | = | 0.002 | uM | ALA4812774 | 8.66 | nM | Plasmodium berghei | ||
| 10. | ALA4876457 | 98; DSM846 | EC50 | > | 20 | uM | ALA4812773 | nM | Plasmodium falciparum | |||
| 11. | ALA4876457 | 98; DSM846 | EC50 | > | 20 | uM | ALA4812772 | nM | Plasmodium falciparum | |||
| 12. | ALA4876457 | 98; DSM846 | EC50 | = | 0.006 | uM | ALA4812771 | 8.24 | nM | Plasmodium falciparum | ||
| 13. | ALA4876457 | 98; DSM846 | F | = | 73 | % | ALA4812770 | % | ||||
| 14. | ALA4876457 | 98; DSM846 | AUC | = | 42 | uM.hr | ALA4812769 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 15. | ALA4876457 | 98; DSM846 | Cmax | = | 6.2 | uM | ALA4812768 | nM | ||||
| 16. | ALA4876457 | 98; DSM846 | Tmax | = | 1 | hr | ALA4812767 | hr | ||||
| 17. | ALA4876457 | 98; DSM846 | t1/2(app) | = | 3.8 | hr | ALA4812766 | hr | ||||
| 18. | ALA4876457 | 98; DSM846 | F | = | 70 | % | ALA4812730 | % | ||||
| 19. | ALA4876457 | 98; DSM846 | AUC | = | 18.3 | uM.hr | ALA4812729 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 20. | ALA4876457 | 98; DSM846 | Cmax | = | 2.1 | uM | ALA4812728 | nM |
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