# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4876497 | 37 | Activity | = | 22.1 | g | ALA4841333 | g | ||||
2. | ALA4876497 | 37 | INH | = | 77.4 | % | ALA4841332 | % | Homo sapiens | |||
3. | ALA4876497 | 37 | Activity | = | 2.86 | mm3 | ALA4841331 | mm3 | Homo sapiens | |||
4. | ALA4876497 | 37 | Activity | = | 371 | mm3 | ALA4841330 | mm3 | Homo sapiens | |||
5. | ALA4876497 | 37 | Activity | < | 10 | % | ALA4841329 | % | ||||
6. | ALA4876497 | 37 | T/C | = | 27.8 | % | ALA4841328 | % | Homo sapiens | |||
7. | ALA4876497 | 37 | CL | = | 60 | ml/min.Kg | ALA4841327 | mL.min-1.kg-1 | ||||
8. | ALA4876497 | 37 | t1/2 | = | 1.81 | hr | ALA4841326 | hr | ||||
9. | ALA4876497 | 37 | MRT | = | 0.73 | hr | ALA4841325 | hr | ||||
10. | ALA4876497 | 37 | AUC | = | 558 | hr.ng/ml | ALA4841324 | ng.hr.mL-1 | ||||
11. | ALA4876497 | 37 | AUClast | = | 553 | hr.ng/ml | ALA4841323 | ng.hr.mL-1 | ||||
12. | ALA4876497 | 37 | F | = | 33.7 | % | ALA4841322 | % | ||||
13. | ALA4876497 | 37 | t1/2 | = | 8.02 | hr | ALA4841321 | hr | ||||
14. | ALA4876497 | 37 | MRT | = | 5.99 | hr | ALA4841320 | hr | ||||
15. | ALA4876497 | 37 | AUC | = | 1881 | hr.ng/ml | ALA4841319 | ng.hr.mL-1 | ||||
16. | ALA4876497 | 37 | AUClast | = | 1759 | hr.ng/ml | ALA4841318 | ng.hr.mL-1 | ||||
17. | ALA4876497 | 37 | Cmax | = | 1573 | ng/ml | ALA4841317 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
18. | ALA4876497 | 37 | Activity | = | 3.59 | % | ALA4841316 | % | Homo sapiens | |||
19. | ALA4876497 | 37 | Activity | = | 16.89 | % | ALA4841315 | % | Homo sapiens | |||
20. | ALA4876497 | 37 | Activity | = | 3.23 | % | ALA4841314 | % | Homo sapiens |