| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4877124 | 17 | F | = | 83 | % | ALA4831670 | % | ||||
| 2. | ALA4877124 | 17 | t1/2 | = | 21 | hr | ALA4831669 | hr | ||||
| 3. | ALA4877124 | 17 | AUC | = | 9.8 | uM.hr | ALA4831668 | standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | standard_value was converted from uM.hr to ug.hr.mL-1 using the parent compound MW | ng.hr.mL-1 | |||
| 4. | ALA4877124 | 17 | Cmax | = | 1.5 | uM | ALA4831667 | nM | ||||
| 5. | ALA4877124 | 17 | t1/2 | = | 2.7 | hr | ALA4831666 | hr | ||||
| 6. | ALA4877124 | 17 | Vdss | = | 1.24 | L/Kg | ALA4831665 | L.kg-1 | ||||
| 7. | ALA4877124 | 17 | CL | = | 20 | uL/min/kg | ALA4831664 | mL.min-1.kg-1 | ||||
| 8. | ALA4877124 | 17 | CLH | = | 199 | microL/min/mg | ALA4831663 | mL.min-1.g-1 | ||||
| 9. | ALA4877124 | 17 | CLH | = | 31 | microL/min/mg | ALA4831662 | mL.min-1.g-1 | ||||
| 10. | ALA4877124 | 17 | PPB | > | 99.6 | % | ALA4831661 | % | ||||
| 11. | ALA4877124 | 17 | Papp | < | 0.1 | 10^-6 cm/s | ALA4831660 | 10^-6 cm/s | ||||
| 12. | ALA4877124 | 17 | solubility | < | 0.2 | uM | ALA4831659 | nM | ||||
| 13. | ALA4877124 | 17 | DC50 | = | 0.004 | uM | ALA4831643 | uM | Homo sapiens | |||
| 14. | ALA4877124 | 17 | GI50 | = | 0.165 | uM | ALA4831640 | nM | Homo sapiens | |||
| 15. | ALA4877124 | 17 | GI50 | > | 10 | uM | ALA4831639 | nM | Homo sapiens | |||
| 16. | ALA4877124 | 17 | IC50 | = | 269 | nM | ALA4831638 | 6.57 | nM | Homo sapiens | ||
| 17. | ALA4877124 | 17 | IC50 | = | 170 | nM | ALA4831637 | 6.77 | nM | Homo sapiens | ||
| 18. | ALA4877124 | 17 | IC50 | = | 332 | nM | ALA4831636 | 6.48 | nM | Homo sapiens | ||
| 19. | ALA4877124 | 17 | IC50 | = | 17 | nM | ALA4831635 | 7.77 | nM | Homo sapiens |
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