| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4877440 | 30 | F | = | 3.2 | % | ALA4845023 | % | ||||
| 2. | ALA4877440 | 30 | AUCt/dose | = | 91 | ng/mL.hr | ALA4845022 | ng/mL.hr | ||||
| 3. | ALA4877440 | 30 | Tmax | = | 2.7 | hr | ALA4845021 | hr | ||||
| 4. | ALA4877440 | 30 | Cmax/dose | = | 10.6 | ng/ml | ALA4845020 | ng/ml | ||||
| 5. | ALA4877440 | 30 | t1/2 | = | 4 | hr | ALA4845019 | hr | ||||
| 6. | ALA4877440 | 30 | AUCt/dose | = | 2842 | ng/mL.hr | ALA4845018 | ng/mL.hr | ||||
| 7. | ALA4877440 | 30 | Vdss | = | 0.7 | L/Kg | ALA4845017 | L.kg-1 | ||||
| 8. | ALA4877440 | 30 | CL | = | 5.6 | ml/min.Kg | ALA4845016 | mL.min-1.kg-1 | ||||
| 9. | ALA4877440 | 30 | t1/2 | = | 1.6 | hr | ALA4845015 | hr | ||||
| 10. | ALA4877440 | 30 | EC50 | = | 23 | nM | ALA4845014 | 7.64 | nM | Mus musculus | ||
| 11. | ALA4877440 | 30 | EC50 | = | 23 | nM | ALA4845013 | 7.64 | nM | Mus musculus | ||
| 12. | ALA4877440 | 30 | IC50 | = | 22.2 | nM | ALA4845012 | 7.65 | nM | Homo sapiens | ||
| 13. | ALA4877440 | 30 | IC50 | > | 10 | uM | ALA4845011 | nM | Homo sapiens | |||
| 14. | ALA4877440 | 30 | INH | = | 34 | % | ALA4845010 | % | Homo sapiens | |||
| 15. | ALA4877440 | 30 | INH | = | 23 | % | ALA4845009 | % | Homo sapiens | |||
| 16. | ALA4877440 | 30 | IC50 | = | 14.1 | nM | ALA4845008 | 7.85 | nM | Homo sapiens |
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