Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA4877846	30	T>IC50	=	16	hr	ALA4822498			hr
2.	ALA4877846	30	IC50	=	11	nM	ALA4822497	7.96		nM	Rattus norvegicus
3.	ALA4877846	30	IC50	=	90.73	nM	ALA4822493	7.04		nM	Homo sapiens
4.	ALA4877846	30	IC50	=	60.08	nM	ALA4822492	7.22		nM	Homo sapiens
5.	ALA4877846	30	IC50	=	27.12	nM	ALA4822491	7.57		nM	Homo sapiens
6.	ALA4877846	30	IC50	=	5.36	nM	ALA4822490	8.27		nM	Homo sapiens
7.	ALA4877846	30	IC50	=	4.15	nM	ALA4822489	8.38		nM	Homo sapiens
8.	ALA4877846	30	Drug metabolism		0		ALA4822488		Metabolite_Notdetected		Homo sapiens
9.	ALA4877846	30	solubility	=	33	ug ml-1	ALA4822486			ug.mL-1
10.	ALA4877846	30	Drug metabolism		0		ALA4822485		Metabolite_Detected		Homo sapiens
11.	ALA4877846	30	T>IC50	=	24	hr	ALA4822484			hr
12.	ALA4877846	30	Activity		0		ALA4822482		Active		Rattus norvegicus
13.	ALA4877846	30	Activity		0		ALA4822481		Active		Rattus norvegicus
14.	ALA4877846	30	Vdss	=	2.62	L/Kg	ALA4822480			L.kg-1
15.	ALA4877846	30	CL	=	2.42	L/kg/hr	ALA4822479			mL.min-1.kg-1
16.	ALA4877846	30	t1/2	=	1.93	hr	ALA4822478			hr
17.	ALA4877846	30	F	=	77	%	ALA4822477			%
18.	ALA4877846	30	Cmax	=	849	ng/ml	ALA4822476		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
19.	ALA4877846	30	AUC	=	79	ng/L.hr	ALA4822475			ng.hr.mL-1
20.	ALA4877846	30	AUC	=	3030	ng/L.hr	ALA4822474			ng.hr.mL-1