| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA4877883 | 15; JH-XVI-178 | F | = | 8 | % | ALA4828676 | % | ||||
| 2. | ALA4877883 | 15; JH-XVI-178 | Vdss | = | 0.8 | L/Kg | ALA4828675 | L.kg-1 | ||||
| 3. | ALA4877883 | 15; JH-XVI-178 | CL | = | 17 | ml/min.Kg | ALA4828674 | mL.min-1.kg-1 | ||||
| 4. | ALA4877883 | 15; JH-XVI-178 | t1/2 | = | 1.3 | hr | ALA4828673 | hr | ||||
| 5. | ALA4877883 | 15; JH-XVI-178 | AUC | = | 51863 | min.ng/ml | ALA4828672 | ng.hr.mL-1 | ||||
| 6. | ALA4877883 | 15; JH-XVI-178 | Cmax | = | 104 | uM | ALA4828671 | nM | ||||
| 7. | ALA4877883 | 15; JH-XVI-178 | CLH | = | 15 | uL/min.mg | ALA4828670 | mL.min-1.g-1 | ||||
| 8. | ALA4877883 | 15; JH-XVI-178 | t1/2 | = | 46 | min | ALA4828669 | hr | ||||
| 9. | ALA4877883 | 15; JH-XVI-178 | IC50 | = | 107 | nM | ALA4828668 | 6.97 | nM | Homo sapiens | ||
| 10. | ALA4877883 | 15; JH-XVI-178 | INH | 0 | ALA4828667 | Active | % | Homo sapiens | ||||
| 11. | ALA4877883 | 15; JH-XVI-178 | INH | 0 | ALA4828666 | Active | % | Homo sapiens | ||||
| 12. | ALA4877883 | 15; JH-XVI-178 | IC50 | = | 2 | nM | ALA4828665 | 8.70 | nM | Homo sapiens | ||
| 13. | ALA4877883 | 15; JH-XVI-178 | IC50 | = | 2 | nM | ALA4828664 | 8.70 | nM | Homo sapiens | ||
| 14. | ALA4877883 | 15; JH-XVI-178 | IC50 | = | 1 | nM | ALA4828663 | 9.00 | nM | Homo sapiens |
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