# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4878004 | 3k | F | = | 69 | % | ALA4835470 | % | ||||
2. | ALA4878004 | 3k | t1/2 | = | 1.7 | hr | ALA4835469 | hr | ||||
3. | ALA4878004 | 3k | Vdu | = | 1.9 | L/Kg | ALA4835468 | L.kg-1 | ||||
4. | ALA4878004 | 3k | Vd | = | 1.4 | L/Kg | ALA4835467 | L.kg-1 | ||||
5. | ALA4878004 | 3k | CL | = | 19 | ml/min.kg | ALA4835466 | mL.min-1.kg-1 | ||||
6. | ALA4878004 | 3k | CL | = | 9 | ml/min.kg | ALA4835465 | mL.min-1.kg-1 | ||||
7. | ALA4878004 | 3k | F | = | 16 | % | ALA4835462 | % | ||||
8. | ALA4878004 | 3k | t1/2 | = | 4 | hr | ALA4835461 | hr | ||||
9. | ALA4878004 | 3k | Vdu | = | 4.8 | L/Kg | ALA4835460 | L.kg-1 | ||||
10. | ALA4878004 | 3k | Vd | = | 0.7 | L/Kg | ALA4835459 | L.kg-1 | ||||
11. | ALA4878004 | 3k | CL | = | 93 | ml/min.kg | ALA4835458 | mL.min-1.kg-1 | ||||
12. | ALA4878004 | 3k | CL | = | 11 | ml/min.kg | ALA4835457 | mL.min-1.kg-1 | ||||
13. | ALA4878004 | 3k | logD | = | 0.7 | ALA4835456 | ||||||
14. | ALA4878004 | 3k | Papp | = | 10 | 10^-6 cm/s | ALA4835455 | 10^-6 cm/s | ||||
15. | ALA4878004 | 3k | IC50 | = | 9 | nM | ALA4835454 | 8.05 | nM | Homo sapiens | ||
16. | ALA4878004 | 3k | IC50 | = | 4.7 | uM | ALA4835453 | 5.33 | nM | |||
17. | ALA4878004 | 3k | IC50 | = | 67 | nM | ALA4835452 | 7.17 | nM | Homo sapiens | ||
18. | ALA4878004 | 3k | Ratio IC50 | = | 150 | ALA4835451 | ||||||
19. | ALA4878004 | 3k | IC50 | = | 0.7 | nM | ALA4835450 | 9.15 | nM | Homo sapiens |