# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4878302 | 14 | F | = | 25 | % | ALA4825915 | % | ||||
2. | ALA4878302 | 14 | Vdss | = | 54.3 | L/Kg | ALA4825914 | L.kg-1 | ||||
3. | ALA4878302 | 14 | CL | = | 174 | ml/min.kg | ALA4825913 | mL.min-1.kg-1 | ||||
4. | ALA4878302 | 14 | Cmax | = | 44.2 | ng/ml | ALA4825912 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA4878302 | 14 | CLH | = | 43.1 | uL/min | ALA4825911 | uL/min | ||||
6. | ALA4878302 | 14 | Ratio | = | 88 | ALA4825910 | ||||||
7. | ALA4878302 | 14 | Papp | = | 0.75 | 10^-6 cm/s | ALA4825909 | 10^-6 cm/s | ||||
8. | ALA4878302 | 14 | Papp | = | 0.75 | 10^-6 cm/s | ALA4825908 | 10^-6 cm/s | ||||
9. | ALA4878302 | 14 | Therm_solubility | = | 176.3 | uM | ALA4825907 | nM | ||||
10. | ALA4878302 | 14 | IC50 | = | 0.5 | nM | ALA4825906 | 9.30 | nM | Human respiratory syncytial virus A (strain A2) | ||
11. | ALA4878302 | 14 | CLH | = | 50.7 | uL/min | ALA4825896 | uL/min | ||||
12. | ALA4878302 | 14 | CLH | = | 6.23 | uL/min | ALA4825895 | uL/min | ||||
13. | ALA4878302 | 14 | CLH | = | 45 | uL/min | ALA4825894 | uL/min | ||||
14. | ALA4878302 | 14 | Fu | = | 18.4 | % | ALA4825893 | |||||
15. | ALA4878302 | 14 | Fu | = | 15.1 | % | ALA4825892 | |||||
16. | ALA4878302 | 14 | Fu | = | 33.3 | % | ALA4825891 | |||||
17. | ALA4878302 | 14 | CC50 | = | 3000 | nM | ALA4825888 | nM | Chlorocebus sabaeus | |||
18. | ALA4878302 | 14 | EC50 | = | 0.8 | nM | ALA4825887 | 9.10 | nM | Human orthopneumovirus |