# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA4878878 | 5; K1576 | Activity | 0 | ALA4818736 | Active | ||||||
2. | ALA4878878 | 5; K1576 | Activity | 0 | ALA4818735 | Not Active | Rattus norvegicus | |||||
3. | ALA4878878 | 5; K1576 | Drug uptake | = | 218 | nM | ALA4818734 | nM | ||||
4. | ALA4878878 | 5; K1576 | Cp | = | 170 | nM | ALA4818733 | nM | ||||
5. | ALA4878878 | 5; K1576 | Drug uptake | = | 1376 | nM | ALA4818732 | nM | ||||
6. | ALA4878878 | 5; K1576 | IC50 | = | 12.75 | uM | ALA4818731 | 4.89 | nM | Rattus norvegicus | ||
7. | ALA4878878 | 5; K1576 | IC50 | = | 45.89 | uM | ALA4818730 | 4.34 | nM | Homo sapiens | ||
8. | ALA4878878 | 5; K1576 | Selectivity Index | = | 4.34 | ALA4818729 | ||||||
9. | ALA4878878 | 5; K1576 | INH | = | 90.95 | % | ALA4818728 | % | Rattus norvegicus | |||
10. | ALA4878878 | 5; K1576 | INH | = | 79.33 | % | ALA4818727 | % | Homo sapiens | |||
11. | ALA4878878 | 5; K1576 | IC50 | = | 7.8 | uM | ALA4818726 | 5.11 | nM | Rattus norvegicus | ||
12. | ALA4878878 | 5; K1576 | Activity | 0 | ALA4818725 | Non-Toxic | ||||||
13. | ALA4878878 | 5; K1576 | IC50 | = | 6.58 | uM | ALA4818724 | 5.18 | nM | Homo sapiens | ||
14. | ALA4878878 | 5; K1576 | Cp | = | 1334 | nM | ALA4818723 | nM | ||||
15. | ALA4878878 | 5; K1576 | BBR | = | 103 | ALA4818721 | ||||||
16. | ALA4878878 | 5; K1576 | IC50 | = | 20.8 | uM | ALA4818720 | 4.68 | nM | Homo sapiens | ||
17. | ALA4878878 | 5; K1576 | IC50 | = | 4.79 | uM | ALA4818719 | 5.32 | nM | Homo sapiens |