# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA352441 | 19 (P44) | IC50 | = | 2 | uM | ALA1217000 | 5.70 | nM | Plasmodium falciparum | ||
2. | ALA352441 | 19 (P44) | Safety ratio | = | 0.6 | ALA841246 | Chlorocebus sabaeus | |||||
3. | ALA352441 | 19 (P44) | Safety ratio | = | 1.9 | ALA838937 | ||||||
4. | ALA352441 | 19 (P44) | Safety ratio | = | 1.9 | ALA841243 | ||||||
5. | ALA352441 | 19 (P44) | IC50 | = | 3.6 | uM | ALA651284 | 5.44 | nM | |||
6. | ALA352441 | 19 (P44) | Safety ratio | = | 0.3 | ALA841247 | Homo sapiens | |||||
7. | ALA352441 | 19 (P44) | Safety ratio | = | 0.8 | ALA838938 | Homo sapiens | |||||
8. | ALA352441 | 19 (P44) | Safety ratio | = | 0.8 | ALA841244 | Homo sapiens | |||||
9. | ALA352441 | 19 (P44) | IC50 | = | 1.6 | uM | ALA704856 | 5.80 | nM | Homo sapiens | ||
10. | ALA352441 | 19 (P44) | Safety ratio | = | 0.9 | ALA841248 | Chlorocebus sabaeus | |||||
11. | ALA352441 | 19 (P44) | Safety ratio | = | 2.7 | ALA841242 | Chlorocebus sabaeus | |||||
12. | ALA352441 | 19 (P44) | Safety ratio | = | 2.7 | ALA841249 | Chlorocebus sabaeus | |||||
13. | ALA352441 | 19 (P44) | IC50 | = | 5.2 | uM | ALA812732 | 5.28 | nM | Chlorocebus sabaeus | ||
14. | ALA352441 | 19 (P44) | IC50 | = | 5.9 | uM | ALA765484 | 5.23 | nM | Plasmodium falciparum K1 | ||
15. | ALA352441 | 19 (P44) | IC50 | = | 1.9 | uM | ALA760860 | 5.72 | nM | Plasmodium falciparum K1 | ||
16. | ALA352441 | 19 (P44) | IC50 | = | 4.1 | uM | ALA765485 | 5.39 | nM | Plasmodium falciparum K1 | ||
17. | ALA352441 | 19 (P44) | IC50 | = | 1.9 | uM | ALA765486 | 5.72 | nM | Plasmodium falciparum K1 | ||
18. | ALA352441 | 19 (P44) | Ratio | = | 3 | ALA847344 | Plasmodium falciparum K1 | |||||
19. | ALA352441 | 19 (P44) | Ki | = | 3.6 | nM | ALA880697 | 8.44 | nM | Plasmodium falciparum K1 | ||
20. | ALA352441 | 19 (P44) | Ratio | = | 0.7 | ALA847342 | Plasmodium falciparum K1 |