# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA444605 | 15 (P42) | IC50 | = | 2 | uM | ALA1217000 | 5.70 | nM | Plasmodium falciparum | ||
2. | ALA444605 | 15 (P42) | Safety ratio | = | 1.9 | ALA841246 | Chlorocebus sabaeus | |||||
3. | ALA444605 | 15 (P42) | Safety ratio | = | 5.6 | ALA838937 | ||||||
4. | ALA444605 | 15 (P42) | Safety ratio | = | 6.3 | ALA841243 | ||||||
5. | ALA444605 | 15 (P42) | IC50 | = | 10 | uM | ALA651284 | 5.00 | nM | |||
6. | ALA444605 | 15 (P42) | Safety ratio | = | 3.2 | ALA841247 | Homo sapiens | |||||
7. | ALA444605 | 15 (P42) | Safety ratio | = | 9.4 | ALA838938 | Homo sapiens | |||||
8. | ALA444605 | 15 (P42) | Safety ratio | = | 10.6 | ALA841244 | Homo sapiens | |||||
9. | ALA444605 | 15 (P42) | IC50 | = | 17 | uM | ALA704856 | 4.77 | nM | Homo sapiens | ||
10. | ALA444605 | 15 (P42) | Safety ratio | = | 9.4 | ALA841248 | Chlorocebus sabaeus | |||||
11. | ALA444605 | 15 (P42) | Safety ratio | = | 27.8 | ALA841242 | Chlorocebus sabaeus | |||||
12. | ALA444605 | 15 (P42) | Safety ratio | = | 31.3 | ALA841249 | Chlorocebus sabaeus | |||||
13. | ALA444605 | 15 (P42) | IC50 | = | 50 | uM | ALA812732 | 4.30 | nM | Chlorocebus sabaeus | ||
14. | ALA444605 | 15 (P42) | IC50 | = | 5.3 | uM | ALA765484 | 5.28 | nM | Plasmodium falciparum K1 | ||
15. | ALA444605 | 15 (P42) | IC50 | = | 1.8 | uM | ALA760860 | 5.75 | nM | Plasmodium falciparum K1 | ||
16. | ALA444605 | 15 (P42) | IC50 | = | 2.1 | uM | ALA765485 | 5.68 | nM | Plasmodium falciparum K1 | ||
17. | ALA444605 | 15 (P42) | IC50 | = | 1.6 | uM | ALA765486 | 5.80 | nM | Plasmodium falciparum K1 | ||
18. | ALA444605 | 15 (P42) | Ratio | = | 10.1 | ALA847344 | Plasmodium falciparum K1 | |||||
19. | ALA444605 | 15 (P42) | Ki | = | 31.4 | nM | ALA880697 | 7.50 | nM | Plasmodium falciparum K1 | ||
20. | ALA444605 | 15 (P42) | Ratio | = | 1 | ALA847342 | Plasmodium falciparum K1 |