# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA346963 | 42 (C372) | IC50 | = | 0 | uM | ALA1217000 | nM | Plasmodium falciparum | |||
2. | ALA346963 | 42 (C372) | Safety ratio | = | 0.7 | ALA841246 | Chlorocebus sabaeus | |||||
3. | ALA346963 | 42 (C372) | Safety ratio | = | 12.9 | ALA838937 | ||||||
4. | ALA346963 | 42 (C372) | Safety ratio | = | 45 | ALA841243 | ||||||
5. | ALA346963 | 42 (C372) | IC50 | = | 1.8 | uM | ALA651284 | 5.75 | nM | |||
6. | ALA346963 | 42 (C372) | Safety ratio | = | 0.4 | ALA841247 | Homo sapiens | |||||
7. | ALA346963 | 42 (C372) | Safety ratio | = | 7.1 | ALA838938 | Homo sapiens | |||||
8. | ALA346963 | 42 (C372) | Safety ratio | = | 25 | ALA841244 | Homo sapiens | |||||
9. | ALA346963 | 42 (C372) | IC50 | = | 1 | uM | ALA704856 | 6.00 | nM | Homo sapiens | ||
10. | ALA346963 | 42 (C372) | Safety ratio | > | 20 | ALA841248 | Chlorocebus sabaeus | |||||
11. | ALA346963 | 42 (C372) | Safety ratio | > | 357 | ALA841242 | Chlorocebus sabaeus | |||||
12. | ALA346963 | 42 (C372) | Safety ratio | > | 1250 | ALA841249 | Chlorocebus sabaeus | |||||
13. | ALA346963 | 42 (C372) | IC50 | > | 50 | uM | ALA812732 | nM | Chlorocebus sabaeus | |||
14. | ALA346963 | 42 (C372) | IC50 | = | 2.5 | uM | ALA765484 | 5.60 | nM | Plasmodium falciparum K1 | ||
15. | ALA346963 | 42 (C372) | IC50 | = | 0.14 | uM | ALA760860 | 6.85 | nM | Plasmodium falciparum K1 | ||
16. | ALA346963 | 42 (C372) | IC50 | = | 0.33 | uM | ALA765485 | 6.48 | nM | Plasmodium falciparum K1 | ||
17. | ALA346963 | 42 (C372) | IC50 | = | 0.26 | uM | ALA760283 | 6.58 | nM | Plasmodium falciparum K1 | ||
18. | ALA346963 | 42 (C372) | IC50 | = | 0.004 | uM | ALA760281 | 8.40 | nM | Plasmodium falciparum K1 | ||
19. | ALA346963 | 42 (C372) | IC50 | = | 0.04 | uM | ALA765486 | 7.40 | nM | Plasmodium falciparum K1 | ||
20. | ALA346963 | 42 (C372) | Ratio | = | 1.4 | ALA847341 | Plasmodium falciparum K1 |