Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA627	Amitriptyline N-oxide	IC50	=	10000	nM	ALA3706031	5.00	234056	nM	Homo sapiens
2.	ALA627	Amitriptyline N-oxide	Activity		0		ALA4614179		Bld		Homo sapiens
3.	ALA627	Amitriptyline N-oxide	Activity	=	3.1	nmol/mg.min	ALA4614174			nmol/mg.min	Homo sapiens
4.	ALA627	Amitriptyline N-oxide	Activity	=	9.5	nmol/mg.min	ALA4614164			nmol/mg.min	Homo sapiens
5.	ALA627	Amitriptyline N-oxide	Activity		0		ALA4614169		Bld		Homo sapiens
6.	ALA627	Amitriptyline N-oxide	Potency	=	1.259	um	ALA1613886	5.90	Active	nM	Homo sapiens
7.	ALA627	Amitriptyline N-oxide	Potency	=	1.259	um	ALA1614108	5.90	Not Active	nM	Homo sapiens
8.	ALA627	Amitriptyline N-oxide	AC50	=	1.259	uM	ALA1741324	5.90	Active	nM	Homo sapiens
9.	ALA627	Amitriptyline N-oxide	AC50	=	0.398	uM	ALA1741323	6.40	Active	nM	Homo sapiens
10.	ALA627	Amitriptyline N-oxide	AC50		0		ALA1741321		inactive		Homo sapiens
11.	ALA627	Amitriptyline N-oxide	AC50	=	0.794	uM	ALA1741322	6.10	inconclusive	nM	Homo sapiens
12.	ALA627	Amitriptyline N-oxide	AC50		0		ALA1741325		inactive		Homo sapiens
13.	ALA627	Amitriptyline N-oxide	Potency	=	0.398	um	ALA1613777	6.40	Active	nM	Homo sapiens
14.	ALA627	Amitriptyline N-oxide	pKa		0		ALA635170		Not Active
15.	ALA627	Amitriptyline N-oxide	Fu	=	0.2		ALA618310
16.	ALA627	Amitriptyline N-oxide	Vdss	=	1.2	l kg-1	ALA624569			L.kg-1