Activities

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Activities

Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	ALA5075135	15; TO-317	IC50	>	50	uM	ALA5042636			nM
2.	ALA5075135	15; TO-317	IC50	=	3.5	uM	ALA5042635	5.46		nM	Homo sapiens
3.	ALA5075135	15; TO-317	IC50	=	0.3	uM	ALA5042634	6.52		nM	Homo sapiens
4.	ALA5075135	15; TO-317	IC50	=	1.7	uM	ALA5042633	5.77		nM	Homo sapiens
5.	ALA5075135	15; TO-317	IC50	=	1.5	uM	ALA5042632	5.82		nM
6.	ALA5075135	15; TO-317	IC50	=	3.3	uM	ALA5042631	5.48		nM	Homo sapiens
7.	ALA5075135	15; TO-317	IC50	=	1.9	uM	ALA5042630	5.72		nM	Homo sapiens
8.	ALA5075135	15; TO-317	IC50	=	0.6	uM	ALA5042629	6.22		nM	Homo sapiens
9.	ALA5075135	15; TO-317	IC50	=	2	uM	ALA5042628	5.70		nM	Homo sapiens
10.	ALA5075135	15; TO-317	IC50	=	2	uM	ALA5042627	5.70		nM	Homo sapiens
11.	ALA5075135	15; TO-317	IC50	=	0.7	uM	ALA5042626	6.16		nM	Homo sapiens
12.	ALA5075135	15; TO-317	IC50	=	0.7	uM	ALA5042625	6.16		nM	Homo sapiens
13.	ALA5075135	15; TO-317	Time	=	142	min	ALA5042624			hr	Homo sapiens
14.	ALA5075135	15; TO-317	log Pe	=	-6		ALA5042623
15.	ALA5075135	15; TO-317	Kinetic_solubility	=	161.5	uM	ALA5042622			nM
16.	ALA5075135	15; TO-317	Cmax	=	95.1	ng/ml	ALA5042621		standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW \| standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
17.	ALA5075135	15; TO-317	t1/2	=	1.7	hr	ALA5042620			hr
18.	ALA5075135	15; TO-317	t1/2	=	108	min	ALA5042619			hr
19.	ALA5075135	15; TO-317	t1/2	=	110	min	ALA5042618			hr
20.	ALA5075135	15; TO-317	Stability	=	68.9	%	ALA5042617			%