# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5075556 | 54c | CL free | > | 800000 | ml/min.kg | ALA5047455 | mL.min-1.kg-1 | ||||
2. | ALA5075556 | 54c | t1/2 | = | 1.9 | hr | ALA5047446 | hr | ||||
3. | ALA5075556 | 54c | Vdss | = | 9 | L/Kg | ALA5047445 | L.kg-1 | ||||
4. | ALA5075556 | 54c | CL | = | 106 | ml/min.kg | ALA5047444 | mL.min-1.kg-1 | ||||
5. | ALA5075556 | 54c | t1/2 | > | 257 | min | ALA5047443 | hr | ||||
6. | ALA5075556 | 54c | t1/2 | > | 257 | min | ALA5047442 | hr | ||||
7. | ALA5075556 | 54c | fAUC | = | 70.3 | ng.hr/g | ALA5047441 | ng.hr/g | ||||
8. | ALA5075556 | 54c | Drug uptake | = | 98.7 | % | ALA5047440 | % | ||||
9. | ALA5075556 | 54c | CLH | = | 17 | ml/min/g | ALA5047439 | mL.min-1.g-1 | ||||
10. | ALA5075556 | 54c | CLH | = | 43 | ml/min/g | ALA5047438 | mL.min-1.g-1 | ||||
11. | ALA5075556 | 54c | CLH | = | 2.6 | ml/min/g | ALA5047437 | mL.min-1.g-1 | ||||
12. | ALA5075556 | 54c | CLH | = | 4.4 | ml/min/g | ALA5047436 | mL.min-1.g-1 | ||||
13. | ALA5075556 | 54c | pIC50 | = | 7.7 | ALA5047435 | 7.70 | nM | Homo sapiens | |||
14. | ALA5075556 | 54c | pIC50 | = | 7.2 | ALA5047434 | 7.20 | nM | Homo sapiens | |||
15. | ALA5075556 | 54c | permeability | = | 133 | nm/s | ALA5047433 | nm/s | ||||
16. | ALA5075556 | 54c | solubility | = | 275 | ug ml-1 | ALA5047432 | ug.mL-1 | ||||
17. | ALA5075556 | 54c | pIC50 | = | 7 | ALA5047431 | 7.00 | nM | Homo sapiens | |||
18. | ALA5075556 | 54c | pIC50 | = | 7.7 | ALA5047429 | 7.70 | nM | Homo sapiens | |||
19. | ALA5075556 | 54c | pIC50 | = | 9.3 | ALA5047428 | 9.30 | nM | Homo sapiens | |||
20. | ALA5075556 | 54c | pIC50 | = | 9.3 | ALA5047427 | 9.30 | nM | Homo sapiens |