| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5076914 | 7 | Emax | = | 73 | % | ALA5040406 | % | Homo sapiens | |||
| 2. | ALA5076914 | 7 | Emax | = | 69 | % | ALA5040405 | % | Homo sapiens | |||
| 3. | ALA5076914 | 7 | Emax | = | 15 | % | ALA5040404 | % | Homo sapiens | |||
| 4. | ALA5076914 | 7 | MRT(t) | = | 9.2 | hr | ALA5040403 | hr | ||||
| 5. | ALA5076914 | 7 | %AUCextra | = | 18.17 | % | ALA5040402 | % | ||||
| 6. | ALA5076914 | 7 | AUC | = | 34968 | ng.hr/ml | ALA5040401 | ng.hr.mL-1 | ||||
| 7. | ALA5076914 | 7 | AUCt | = | 28615 | ng.hr/ml | ALA5040400 | ng.hr.mL-1 | ||||
| 8. | ALA5076914 | 7 | t1/2 | = | 9.42 | hr | ALA5040399 | hr | ||||
| 9. | ALA5076914 | 7 | Tmax | = | 0.25 | hr | ALA5040398 | hr | ||||
| 10. | ALA5076914 | 7 | Cmax | = | 3608 | ng/ml | ALA5040397 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA5076914 | 7 | EC50 | = | 7.36 | uM | ALA5040396 | 5.13 | nM | Homo sapiens | ||
| 12. | ALA5076914 | 7 | EC50 | = | 1.74 | uM | ALA5040395 | 5.76 | nM | Homo sapiens | ||
| 13. | ALA5076914 | 7 | EC50 | = | 0.3 | uM | ALA5040394 | 6.52 | nM | Homo sapiens | ||
| 14. | ALA5076914 | 7 | EC50 | = | 0.43 | uM | ALA5040393 | 6.37 | nM | Homo sapiens | ||
| 15. | ALA5076914 | 7 | CLH | = | 2 | ml/min/mg | ALA5040392 | mL.min-1.g-1 | ||||
| 16. | ALA5076914 | 7 | CLH | = | 2 | ml/min/mg | ALA5040391 | mL.min-1.g-1 | ||||
| 17. | ALA5076914 | 7 | t1/2 | > | 400 | hr | ALA5040390 | hr | ||||
| 18. | ALA5076914 | 7 | t1/2 | > | 400 | hr | ALA5040389 | hr | ||||
| 19. | ALA5076914 | 7 | logD | > | 4 | ALA5040388 | ||||||
| 20. | ALA5076914 | 7 | Kinetic_solubility | = | 15 | uM | ALA5040387 | nM |
The page will load shortly, Thanks for your patience!