Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	milrebrutinib	13f; AS-1763	INH		0		ALA5054265	Active	%	Mus musculus
2.	milrebrutinib	13f; AS-1763	INH		0		ALA5054264	Active	%	Mus musculus
3.	milrebrutinib	13f; AS-1763	INH		0		ALA5054263	Active	%	Mus musculus
4.	milrebrutinib	13f; AS-1763	Activity		0		ALA5054262	Non-Toxic		Mus musculus
5.	milrebrutinib	13f; AS-1763	TGI	=	73	%	ALA5054261		%	Homo sapiens
6.	milrebrutinib	13f; AS-1763	TGI	=	111.8	%	ALA5054260		%	Homo sapiens
7.	milrebrutinib	13f; AS-1763	TGI	=	81.6	%	ALA5054259		%	Homo sapiens
8.	milrebrutinib	13f; AS-1763	TGI	=	74.5	%	ALA5054258		%	Homo sapiens
9.	milrebrutinib	13f; AS-1763	F	=	68.1	%	ALA5054257		%
10.	milrebrutinib	13f; AS-1763	F	=	15.9	%	ALA5054256		%
11.	milrebrutinib	13f; AS-1763	F	=	60.8	%	ALA5054255		%
12.	milrebrutinib	13f; AS-1763	CL	=	1.36	L/kg/hr	ALA5054254		mL.min-1.kg-1
13.	milrebrutinib	13f; AS-1763	CL	=	1.22	L/kg/hr	ALA5054253		mL.min-1.kg-1
14.	milrebrutinib	13f; AS-1763	CL	=	1.13	L/kg/hr	ALA5054252		mL.min-1.kg-1
15.	milrebrutinib	13f; AS-1763	Vdss	=	1.77	L/Kg	ALA5054251		L.kg-1
16.	milrebrutinib	13f; AS-1763	Vdss	=	3.64	L/Kg	ALA5054250		L.kg-1
17.	milrebrutinib	13f; AS-1763	Vdss	=	1.61	L/Kg	ALA5054249		L.kg-1
18.	milrebrutinib	13f; AS-1763	AUClast	=	2493	ng/mL.hr	ALA5054248		ng.hr.mL-1
19.	milrebrutinib	13f; AS-1763	AUClast	=	734	ng/mL.hr	ALA5054247		ng.hr.mL-1
20.	milrebrutinib	13f; AS-1763	AUClast	=	1872	ng/mL.hr	ALA5054246		ng.hr.mL-1