# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5078647 | 46e | Drug metabolism | 0 | ALA5047459 | Metabolite_Detected | ||||||
2. | ALA5078647 | 46e | Drug metabolism | 0 | ALA5047458 | Metabolite_Notdetected | ||||||
3. | ALA5078647 | 46e | Stability | 0 | ALA5047457 | Stable | % | |||||
4. | ALA5078647 | 46e | Stability | 0 | ALA5047456 | Unstable | % | |||||
5. | ALA5078647 | 46e | Drug metabolism | 0 | ALA5047454 | Metabolite_Notdetected | Mus musculus | |||||
6. | ALA5078647 | 46e | solubility | = | 7 | ug ml-1 | ALA5047453 | ug.mL-1 | ||||
7. | ALA5078647 | 46e | Drug metabolism | 0 | ALA5047452 | Metabolite_Detected | Mus musculus | |||||
8. | ALA5078647 | 46e | solubility | = | 92 | ug ml-1 | ALA5047451 | ug.mL-1 | ||||
9. | ALA5078647 | 46e | t1/2 | > | 257 | min | ALA5047443 | hr | ||||
10. | ALA5078647 | 46e | t1/2 | = | 1 | min | ALA5047442 | hr | ||||
11. | ALA5078647 | 46e | fAUC | = | 3.5 | ng.hr/g | ALA5047441 | ng.hr/g | ||||
12. | ALA5078647 | 46e | Drug uptake | = | 98.7 | % | ALA5047440 | % | ||||
13. | ALA5078647 | 46e | CLH | = | 76 | ml/min/g | ALA5047439 | mL.min-1.g-1 | ||||
14. | ALA5078647 | 46e | CLH | = | 61 | ml/min/g | ALA5047438 | mL.min-1.g-1 | ||||
15. | ALA5078647 | 46e | CLH | = | 7.7 | ml/min/g | ALA5047437 | mL.min-1.g-1 | ||||
16. | ALA5078647 | 46e | CLH | = | 7.8 | ml/min/g | ALA5047436 | mL.min-1.g-1 | ||||
17. | ALA5078647 | 46e | pIC50 | = | 7.4 | ALA5047435 | 7.40 | nM | Homo sapiens | |||
18. | ALA5078647 | 46e | pIC50 | = | 7.1 | ALA5047434 | 7.10 | nM | Homo sapiens | |||
19. | ALA5078647 | 46e | permeability | = | 176 | nm/s | ALA5047433 | nm/s | ||||
20. | ALA5078647 | 46e | pIC50 | = | 6.2 | ALA5047431 | 6.20 | nM | Homo sapiens |