# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5079857 | 44 | Activity | 0 | ALA5047886 | Active | Mycolicibacterium smegmatis | |||||
2. | ALA5079857 | 44 | F | = | 21 | % | ALA5047885 | % | ||||
3. | ALA5079857 | 44 | Tlast | = | 24 | hr | ALA5047884 | hr | ||||
4. | ALA5079857 | 44 | beta t1/2 | = | 6.06 | hr | ALA5047883 | hr | ||||
5. | ALA5079857 | 44 | AUC | = | 215 | hr.ng/ml | ALA5047882 | ng.hr.mL-1 | ||||
6. | ALA5079857 | 44 | AUClast | = | 203 | hr.ng/ml | ALA5047881 | ng.hr.mL-1 | ||||
7. | ALA5079857 | 44 | Cmax | = | 51.6 | ng/ml | ALA5047880 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA5079857 | 44 | CLH | = | 84.8 | ml/min.kg | ALA5047879 | mL.min-1.kg-1 | ||||
9. | ALA5079857 | 44 | Vdss | = | 11.5 | kg/L | ALA5047878 | kg/L | ||||
10. | ALA5079857 | 44 | Tlast | = | 12 | hr | ALA5047877 | hr | ||||
11. | ALA5079857 | 44 | beta t1/2 | = | 4.76 | hr | ALA5047876 | hr | ||||
12. | ALA5079857 | 44 | AUC | = | 197 | hr.ng/ml | ALA5047875 | ng.hr.mL-1 | ||||
13. | ALA5079857 | 44 | AUClast | = | 190 | hr.ng/ml | ALA5047874 | ng.hr.mL-1 | ||||
14. | ALA5079857 | 44 | Cmax | = | 448 | ng/ml | ALA5047873 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
15. | ALA5079857 | 44 | FIC | = | 1.12 | ALA5047872 | Mycolicibacterium smegmatis | |||||
16. | ALA5079857 | 44 | FIC | = | 0.6 | ALA5047871 | Mycolicibacterium smegmatis | |||||
17. | ALA5079857 | 44 | Activity | = | 90 | % | ALA5047870 | % | Mycolicibacterium aurum | |||
18. | ALA5079857 | 44 | Selectivity Index | = | 4 | ALA5047869 | ||||||
19. | ALA5079857 | 44 | Selectivity Index | = | 8 | ALA5047868 | ||||||
20. | ALA5079857 | 44 | Selectivity Index | = | 16 | ALA5047867 |