| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5081174 | 18k | F | = | 81.7 | % | ALA5038334 | % | ||||
| 2. | ALA5081174 | 18k | Vdss | = | 1720 | ml/kg | ALA5038333 | L.kg-1 | ||||
| 3. | ALA5081174 | 18k | AUC | = | 1060 | hr.ng/ml | ALA5038332 | ng.hr.mL-1 | ||||
| 4. | ALA5081174 | 18k | AUCt | = | 929 | hr.ng/ml | ALA5038331 | ng.hr.mL-1 | ||||
| 5. | ALA5081174 | 18k | MRT | = | 3.65 | hr | ALA5038330 | hr | ||||
| 6. | ALA5081174 | 18k | MRT | = | 4.37 | hr | ALA5038329 | hr | ||||
| 7. | ALA5081174 | 18k | CL | = | 7.97 | ml/min.kg | ALA5038328 | mL.min-1.kg-1 | ||||
| 8. | ALA5081174 | 18k | AUC | = | 5219 | hr.ng/ml | ALA5038327 | ng.hr.mL-1 | ||||
| 9. | ALA5081174 | 18k | AUCt | = | 4552 | hr.ng/ml | ALA5038326 | ng.hr.mL-1 | ||||
| 10. | ALA5081174 | 18k | Cmax | = | 288 | ng/ml | ALA5038325 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 11. | ALA5081174 | 18k | Cmax | = | 868 | ng/ml | ALA5038324 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 12. | ALA5081174 | 18k | Tmax | = | 2.67 | hr | ALA5038323 | hr | ||||
| 13. | ALA5081174 | 18k | t1/2 | = | 2.67 | hr | ALA5038322 | hr | ||||
| 14. | ALA5081174 | 18k | t1/2 | = | 2.16 | hr | ALA5038321 | hr | ||||
| 15. | ALA5081174 | 18k | INH | 0 | ALA5038320 | Dose-Dependent Effect | % | Mus musculus | ||||
| 16. | ALA5081174 | 18k | IC50 | = | 2.115 | uM | ALA5038319 | 5.67 | nM | Homo sapiens | ||
| 17. | ALA5081174 | 18k | IC50 | = | 0.603 | uM | ALA5038318 | 6.22 | nM | Homo sapiens | ||
| 18. | ALA5081174 | 18k | IC50 | = | 1.192 | uM | ALA5038317 | 5.92 | nM | Homo sapiens | ||
| 19. | ALA5081174 | 18k | IC50 | = | 1.691 | uM | ALA5038316 | 5.77 | nM | Mus musculus | ||
| 20. | ALA5081174 | 18k | IC50 | = | 0.141 | uM | ALA5038315 | 6.85 | nM | Mus musculus |
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