| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5081803 | 13 | t1/2 | = | 154 | min | ALA5042464 | hr | ||||
| 2. | ALA5081803 | 13 | t1/2 | = | 200 | min | ALA5042463 | hr | ||||
| 3. | ALA5081803 | 13 | CL | = | 8.4 | ml/min.kg | ALA5042462 | mL.min-1.kg-1 | ||||
| 4. | ALA5081803 | 13 | CL | = | 288 | ml/min.kg | ALA5042461 | mL.min-1.kg-1 | ||||
| 5. | ALA5081803 | 13 | Vd | = | 85 | L/Kg | ALA5042460 | L.kg-1 | ||||
| 6. | ALA5081803 | 13 | K(p,uu,brain) | = | 7.8 | ALA5042459 | ||||||
| 7. | ALA5081803 | 13 | Fu | = | 60.7 | ng/ml | ALA5042456 | ng/ml | ||||
| 8. | ALA5081803 | 13 | Fu | = | 7.8 | ng/ml | ALA5042455 | ng/ml | ||||
| 9. | ALA5081803 | 13 | AUC | = | 4929 | hr.ng/ml | ALA5042454 | ng.hr.mL-1 | ||||
| 10. | ALA5081803 | 13 | AUC | = | 144 | hr.ng/ml | ALA5042453 | ng.hr.mL-1 | ||||
| 11. | ALA5081803 | 13 | Cmax | = | 674 | ng/ml | ALA5042452 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 12. | ALA5081803 | 13 | Cmax | = | 27 | ng/ml | ALA5042451 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | ALA5081803 | 13 | Ratio | = | 0.81 | ALA5042450 | ||||||
| 14. | ALA5081803 | 13 | Papp | = | 1.1 | 10^-6 cm/s | ALA5042449 | 10^-6 cm/s | ||||
| 15. | ALA5081803 | 13 | Papp | = | 1.35 | 10^-6 cm/s | ALA5042448 | 10^-6 cm/s | ||||
| 16. | ALA5081803 | 13 | t1/2 | = | 243 | min | ALA5042447 | hr | ||||
| 17. | ALA5081803 | 13 | CLH | = | 5.13 | ml/min.kg | ALA5042446 | mL.min-1.kg-1 | ||||
| 18. | ALA5081803 | 13 | INH | = | 12 | % | ALA5042445 | % | Homo sapiens | |||
| 19. | ALA5081803 | 13 | IC50 | = | 944 | nM | ALA5042444 | 6.03 | nM | Homo sapiens | ||
| 20. | ALA5081803 | 13 | IC50 | = | 24 | nM | ALA5042443 | 7.62 | nM | Homo sapiens |
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