# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA418192 | Tolamolol | pKa | 7.9 | ALA2449009 | Basic pKa | ||||||
2. | ALA418192 | Tolamolol | Potency | 0.455 | uM | ALA1963912 | inconclusive | nM | ||||
3. | ALA418192 | Tolamolol | INH | = | 81 | % | ALA3280055 | % | Felis catus | |||
4. | ALA418192 | Tolamolol | ED50 | = | 133 | ug/kg | ALA3280054 | mg.kg-1 | Felis catus | |||
5. | ALA418192 | Tolamolol | inhibition | = | -0.05 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
6. | ALA418192 | Tolamolol | inhibition | = | -0.03 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
7. | ALA418192 | Tolamolol | Inhibition | = | 4.4 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
8. | ALA418192 | Tolamolol | Inhibition | = | 17.12 | % | ALA4495582 | % | Severe acute respiratory syndrome coronavirus 2 | |||
9. | ALA418192 | Tolamolol | pIC50 | < | 4.7 | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | |||
10. | ALA418192 | Tolamolol | IC50 | > | 0 | M | ALA4651403 | No. Measurements = 1 | nM | Severe acute respiratory syndrome coronavirus 2 | ||
11. | ALA418192 | Tolamolol | inhibition | = | -0.05 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
12. | ALA418192 | Tolamolol | inhibition | = | -0.03 | % | ALA4513082 | % | Severe acute respiratory syndrome coronavirus 2 | |||
13. | ALA418192 | Tolamolol | inhibition | = | -10.6 | % | ALA4808150 | % | Homo sapiens | |||
14. | ALA418192 | Tolamolol | inhibition | = | 0.61 | % | ALA4808149 | % | Homo sapiens | |||
15. | ALA418192 | Tolamolol | Inhibition | = | -8.84 | % | ALA4303805 | % | Severe acute respiratory syndrome coronavirus 2 | |||
16. | ALA418192 | Tolamolol | INH | = | 81 | % | ALA3279118 | % | Felis catus | |||
17. | ALA418192 | Tolamolol | ED50 | = | 133 | ug/kg | ALA3279116 | mg.kg-1 | Felis catus | |||
18. | ALA418192 | Tolamolol | CL | = | 14 | mL/min/kg | ALA1614671 | mL.min-1.kg-1 | ||||
19. | ALA418192 | Tolamolol | MRT | = | 4.8 | h | ALA1614673 | hr | ||||
20. | ALA418192 | Tolamolol | Vdss | = | 4 | L/kg | ALA1614670 | L.kg-1 |