# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5084053 | 38 | Ratio | = | 1.78 | ALA5031950 | ||||||
2. | ALA5084053 | 38 | Ratio | = | 136.6 | ALA5031949 | ||||||
3. | ALA5084053 | 38 | Emax | = | 60 | % | ALA5031944 | % | Rattus norvegicus | |||
4. | ALA5084053 | 38 | ED50 | = | 0.3 | mg kg-1 | ALA5031943 | mg.kg-1 | Rattus norvegicus | |||
5. | ALA5084053 | 38 | Fu | = | 1.3 | % | ALA5031942 | |||||
6. | ALA5084053 | 38 | F | = | 46.9 | % | ALA5031941 | % | ||||
7. | ALA5084053 | 38 | Cmax | = | 597 | ng/ml | ALA5031940 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA5084053 | 38 | AUC | = | 4020 | ng/mL.hr | ALA5031939 | ng.hr.mL-1 | ||||
9. | ALA5084053 | 38 | t1/2 | = | 4.3 | hr | ALA5031938 | hr | ||||
10. | ALA5084053 | 38 | CL | = | 5.9 | ml/min.kg | ALA5031937 | mL.min-1.kg-1 | ||||
11. | ALA5084053 | 38 | IC50 | > | 20 | uM | ALA5031936 | nM | Homo sapiens | |||
12. | ALA5084053 | 38 | IC50 | > | 20 | uM | ALA5031935 | nM | Homo sapiens | |||
13. | ALA5084053 | 38 | IC50 | > | 20 | uM | ALA5031934 | nM | Homo sapiens | |||
14. | ALA5084053 | 38 | IC50 | > | 20 | uM | ALA5031933 | nM | Homo sapiens | |||
15. | ALA5084053 | 38 | IC50 | > | 20 | uM | ALA5031932 | nM | Homo sapiens | |||
16. | ALA5084053 | 38 | solubility | = | 212 | ug ml-1 | ALA5031931 | ug.mL-1 | ||||
17. | ALA5084053 | 38 | solubility | = | 2.2 | ug ml-1 | ALA5031930 | ug.mL-1 | ||||
18. | ALA5084053 | 38 | IC50 | > | 30000 | nM | ALA5031929 | nM | Homo sapiens | |||
19. | ALA5084053 | 38 | IC50 | > | 30000 | nM | ALA5031928 | nM | Homo sapiens | |||
20. | ALA5084053 | 38 | IC50 | > | 30000 | nM | ALA5031927 | nM | Homo sapiens |