# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5085809 | 34 | Tmax | = | 3 | hr | ALA5050820 | hr | ||||
2. | ALA5085809 | 34 | F | = | 21 | % | ALA5050819 | % | ||||
3. | ALA5085809 | 34 | Drug uptake(free) | = | 53.2 | nM | ALA5050818 | nM | ||||
4. | ALA5085809 | 34 | Drug uptake(free) | = | 49.5 | nM | ALA5050817 | nM | ||||
5. | ALA5085809 | 34 | Drug uptake(free) | = | 38.1 | nM | ALA5050816 | nM | ||||
6. | ALA5085809 | 34 | Ct | = | 117 | ng/g | ALA5050815 | ng/g | ||||
7. | ALA5085809 | 34 | Ct | = | 109 | ng/g | ALA5050814 | ng/g | ||||
8. | ALA5085809 | 34 | Ct | = | 83.8 | ng/g | ALA5050813 | ng/g | ||||
9. | ALA5085809 | 34 | Ct | = | 7383 | ng/g | ALA5050812 | ng/g | ||||
10. | ALA5085809 | 34 | Ct | = | 7160 | ng/g | ALA5050811 | ng/g | ||||
11. | ALA5085809 | 34 | Ct | = | 4553 | ng/g | ALA5050810 | ng/g | ||||
12. | ALA5085809 | 34 | Fu | = | 17.5 | % | ALA5050809 | |||||
13. | ALA5085809 | 34 | PPB | = | 17.2 | % | ALA5050808 | % | ||||
14. | ALA5085809 | 34 | Cmax | = | 2960 | ng/ml | ALA5050807 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
15. | ALA5085809 | 34 | Tmax | = | 0.44 | hr | ALA5050806 | hr | ||||
16. | ALA5085809 | 34 | AUClast | = | 7990 | ng/mL.hr | ALA5050805 | ng.hr.mL-1 | ||||
17. | ALA5085809 | 34 | K(p,uu,brain) | = | 0.8 | ALA5050804 | ||||||
18. | ALA5085809 | 34 | Fu | = | 10.8 | % | ALA5050803 | |||||
19. | ALA5085809 | 34 | PPB | = | 36.3 | % | ALA5050802 | % | ||||
20. | ALA5085809 | 34 | IC50 | > | 30 | uM | ALA5050801 | nM | Homo sapiens |