| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5086263 | 10 | IC50 | = | 5 | nM | ALA5046210 | 8.30 | nM | Homo sapiens | ||
| 2. | ALA5086263 | 10 | IC50 | = | 3 | nM | ALA5046209 | 8.52 | nM | Homo sapiens | ||
| 3. | ALA5086263 | 10 | F | = | 12.3 | % | ALA5046208 | % | ||||
| 4. | ALA5086263 | 10 | Cmax | = | 34.1 | uM | ALA5046207 | nM | ||||
| 5. | ALA5086263 | 10 | Cmax | = | 6.4 | uM | ALA5046206 | nM | ||||
| 6. | ALA5086263 | 10 | CL | = | 5.9 | ml/min.kg | ALA5046205 | mL.min-1.kg-1 | ||||
| 7. | ALA5086263 | 10 | CL | = | 29.3 | ml/min.kg | ALA5046204 | mL.min-1.kg-1 | ||||
| 8. | ALA5086263 | 10 | AUC | = | 8947.2 | ng/mL.hr | ALA5046202 | ng.hr.mL-1 | ||||
| 9. | ALA5086263 | 10 | AUC | = | 5770.3 | ng/mL.hr | ALA5046201 | ng.hr.mL-1 | ||||
| 10. | ALA5086263 | 10 | t1/2 | = | 1.2 | hr | ALA5046199 | hr | ||||
| 11. | ALA5086263 | 10 | t1/2 | = | 2.4 | hr | ALA5046198 | hr | ||||
| 12. | ALA5086263 | 10 | Activity | = | 38 | % | ALA5046196 | % | Homo sapiens | |||
| 13. | ALA5086263 | 10 | Activity | = | 10 | % | ALA5046195 | % | Homo sapiens | |||
| 14. | ALA5086263 | 10 | Activity | = | 49 | % | ALA5046194 | % | Homo sapiens | |||
| 15. | ALA5086263 | 10 | Activity | = | 56 | % | ALA5046193 | % | Homo sapiens | |||
| 16. | ALA5086263 | 10 | Activity | = | 63 | % | ALA5046192 | % | Homo sapiens | |||
| 17. | ALA5086263 | 10 | Activity | = | 74 | % | ALA5046191 | % | Homo sapiens | |||
| 18. | ALA5086263 | 10 | Activity | = | 85 | % | ALA5046190 | % | Homo sapiens | |||
| 19. | ALA5086263 | 10 | Activity | = | 81 | % | ALA5046189 | % | Homo sapiens | |||
| 20. | ALA5086263 | 10 | Activity | = | 58 | % | ALA5046188 | % | Homo sapiens |
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