# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5086642 | 34 | IC50 | > | 10 | uM | ALA5034183 | nM | Homo sapiens | |||
2. | ALA5086642 | 34 | Ratio | = | 1.02 | ALA5034182 | ||||||
3. | ALA5086642 | 34 | F | = | 67 | % | ALA5034181 | % | ||||
4. | ALA5086642 | 34 | Cmax | = | 1363 | ng/ml | ALA5034180 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
5. | ALA5086642 | 34 | AUC | = | 1817 | ng/mL.hr | ALA5034179 | ng.hr.mL-1 | ||||
6. | ALA5086642 | 34 | AUC | = | 833 | ng/mL.hr | ALA5034178 | ng.hr.mL-1 | ||||
7. | ALA5086642 | 34 | Tmax | = | 0.5 | hr | ALA5034177 | hr | ||||
8. | ALA5086642 | 34 | t1/2 | = | 0.91 | hr | ALA5034176 | hr | ||||
9. | ALA5086642 | 34 | t1/2 | = | 0.26 | hr | ALA5034175 | hr | ||||
10. | ALA5086642 | 34 | Vd | = | 1.33 | L/Kg | ALA5034174 | L.kg-1 | ||||
11. | ALA5086642 | 34 | CL | = | 60 | ml/min.kg | ALA5034173 | mL.min-1.kg-1 | ||||
12. | ALA5086642 | 34 | IC50 | > | 10 | uM | ALA5034172 | nM | Homo sapiens | |||
13. | ALA5086642 | 34 | IC50 | > | 10 | uM | ALA5034171 | nM | Homo sapiens | |||
14. | ALA5086642 | 34 | IC50 | > | 10 | uM | ALA5034170 | nM | Homo sapiens | |||
15. | ALA5086642 | 34 | IC50 | = | 8.3 | uM | ALA5034169 | 5.08 | nM | Homo sapiens | ||
16. | ALA5086642 | 34 | PPB | = | 92.9 | % | ALA5034168 | % | ||||
17. | ALA5086642 | 34 | PPB | = | 84.8 | % | ALA5034167 | % | ||||
18. | ALA5086642 | 34 | solubility | = | 43 | ug ml-1 | ALA5034166 | ug.mL-1 | ||||
19. | ALA5086642 | 34 | logD | = | 3.09 | ALA5034165 | ||||||
20. | ALA5086642 | 34 | IC50 | = | 25 | uM | ALA5034164 | 4.60 | nM | Homo sapiens |