Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Assay	Assay Organism
1.	ALA5091591	32; EPZ-719	CLH	=	721	ml/min.kg	ALA5125552		mL.min-1.kg-1
2.	ALA5091591	32; EPZ-719	CLH	=	137	ml/min.kg	ALA5125551		mL.min-1.kg-1
3.	ALA5091591	32; EPZ-719	CLH	=	51	ml/min.kg	ALA5125550		mL.min-1.kg-1
4.	ALA5091591	32; EPZ-719	Papp	=	18	10^-6 cm/s	ALA5125549		10^-6 cm/s
5.	ALA5091591	32; EPZ-719	Papp	=	3.2	10^-6 cm/s	ALA5125548		10^-6 cm/s
6.	ALA5091591	32; EPZ-719	EC50	=	0.025	uM	ALA5125547	7.60	nM
7.	ALA5091591	32; EPZ-719	IC50	=	0.02	uM	ALA5125546	7.70	nM	Homo sapiens
8.	ALA5091591	32; EPZ-719	IC50	=	0.008	uM	ALA5125545	8.10	nM	Homo sapiens
9.	ALA5091591	32; EPZ-719	Fa	=	0.7		ALA5040807
10.	ALA5091591	32; EPZ-719	IC50	=	0.025	uM	ALA5040806	7.60	nM
11.	ALA5091591	32; EPZ-719	beta t1/2	=	0.7	hr	ALA5040804		hr
12.	ALA5091591	32; EPZ-719	Vd	=	1.04	L/Kg	ALA5040803		L.kg-1
13.	ALA5091591	32; EPZ-719	CL	=	24.2	ml/min.kg	ALA5040802		mL.min-1.kg-1
14.	ALA5091591	32; EPZ-719	IC50	=	4.5	uM	ALA5040801	5.35	nM	Homo sapiens
15.	ALA5091591	32; EPZ-719	IC50	>	50	uM	ALA5040800		nM	Homo sapiens
16.	ALA5091591	32; EPZ-719	IC50	>	50	uM	ALA5040799		nM	Homo sapiens
17.	ALA5091591	32; EPZ-719	IC50	=	36	uM	ALA5040798	4.44	nM	Homo sapiens
18.	ALA5091591	32; EPZ-719	IC50	=	16	uM	ALA5040797	4.80	nM	Homo sapiens
19.	ALA5091591	32; EPZ-719	IC50	>	50	uM	ALA5040796		nM	Homo sapiens
20.	ALA5091591	32; EPZ-719	IC50	>	50	uM	ALA5040795		nM	Homo sapiens