| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5092471 | 25 | Activity | = | 1 | % | ALA5050646 | % | ||||
| 2. | ALA5092471 | 25 | CLH | = | 58 | ml/min.kg | ALA5050645 | mL.min-1.kg-1 | ||||
| 3. | ALA5092471 | 25 | permeability | = | 38.7 | 10^-6 cm/s | ALA5050644 | 10^-6 cm/s | ||||
| 4. | ALA5092471 | 25 | solubility | = | 123 | uM | ALA5050643 | nM | ||||
| 5. | ALA5092471 | 25 | solubility | = | 154 | uM | ALA5050642 | nM | ||||
| 6. | ALA5092471 | 25 | solubility | = | 143 | uM | ALA5050641 | nM | ||||
| 7. | ALA5092471 | 25 | F | = | 77 | % | ALA5050640 | % | ||||
| 8. | ALA5092471 | 25 | F | = | 100 | % | ALA5050639 | % | ||||
| 9. | ALA5092471 | 25 | CL | = | 26 | ml/min.kg | ALA5050638 | mL.min-1.kg-1 | ||||
| 10. | ALA5092471 | 25 | CL | = | 69 | ml/min.kg | ALA5050637 | mL.min-1.kg-1 | ||||
| 11. | ALA5092471 | 25 | Vd | = | 5.1 | L/Kg | ALA5050636 | L.kg-1 | ||||
| 12. | ALA5092471 | 25 | Vd | = | 3.7 | L/Kg | ALA5050635 | L.kg-1 | ||||
| 13. | ALA5092471 | 25 | t1/2 | = | 6 | hr | ALA5050634 | hr | ||||
| 14. | ALA5092471 | 25 | t1/2 | = | 1.1 | hr | ALA5050633 | hr | ||||
| 15. | ALA5092471 | 25 | Ratio | = | 1.2 | ALA5050632 | Homo sapiens | |||||
| 16. | ALA5092471 | 25 | logD | = | 2.67 | ALA5050630 | ||||||
| 17. | ALA5092471 | 25 | Drug metabolism | = | 1 | % | ALA5050629 | % | ||||
| 18. | ALA5092471 | 25 | Drug metabolism | < | 1 | % | ALA5050627 | % | ||||
| 19. | ALA5092471 | 25 | IC50 | = | 53.6 | nM | ALA5050625 | 7.27 | nM | Homo sapiens | ||
| 20. | ALA5092471 | 25 | IC50 | = | 32.5 | nM | ALA5050624 | 7.49 | nM | Homo sapiens |
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