# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5092908 | 4b | Cmax | = | 40.2 | ng/ml | ALA5046547 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
2. | ALA5092908 | 4b | Cmax | = | 1004.3 | ng/ml | ALA5046546 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
3. | ALA5092908 | 4b | t1/2 | = | 0.9 | hr | ALA5046545 | hr | ||||
4. | ALA5092908 | 4b | t1/2 | = | 1.2 | hr | ALA5046544 | hr | ||||
5. | ALA5092908 | 4b | AUC | = | 3453.5 | hr.ng/ml | ALA5046534 | ng.hr.mL-1 | ||||
6. | ALA5092908 | 4b | AUC | = | 567.3 | hr.ng/ml | ALA5046533 | ng.hr.mL-1 | ||||
7. | ALA5092908 | 4b | Peff | = | 1.23 | 10^-6 cm/s | ALA5046511 | 10^-6 cm/s | ||||
8. | ALA5092908 | 4b | Ratio IC50 | = | 52 | ALA5046510 | ||||||
9. | ALA5092908 | 4b | Ratio IC50 | = | 47 | ALA5046509 | Homo sapiens | |||||
10. | ALA5092908 | 4b | IC50 | = | 46590 | nM | ALA5046508 | 4.33 | nM | Homo sapiens | ||
11. | ALA5092908 | 4b | IC50 | = | 40330 | nM | ALA5046507 | 4.39 | nM | Homo sapiens | ||
12. | ALA5092908 | 4b | IC50 | = | 892 | nM | ALA5046506 | 6.05 | nM | Homo sapiens | ||
13. | ALA5092908 | 4b | Activity | > | 50 | % | ALA5046505 | % | Mus musculus |