# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5093991 | 31b | Kinetic_solubility | = | 13 | uM | ALA5030380 | nM | ||||
2. | ALA5093991 | 31b | CL | = | 0.94 | L/hr/kg | ALA5030379 | mL.min-1.kg-1 | ||||
3. | ALA5093991 | 31b | Vd | = | 0.8 | L/Kg | ALA5030378 | L.kg-1 | ||||
4. | ALA5093991 | 31b | MRT | = | 1.47 | hr | ALA5030377 | hr | ||||
5. | ALA5093991 | 31b | AUC | = | 5316 | ng/mL.hr | ALA5030376 | ng.hr.mL-1 | ||||
6. | ALA5093991 | 31b | AUCt | = | 5313 | ng/mL.hr | ALA5030375 | ng.hr.mL-1 | ||||
7. | ALA5093991 | 31b | Cmax | = | 5796 | ng/ml | ALA5030374 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
8. | ALA5093991 | 31b | Tmax | = | 0.25 | hr | ALA5030373 | hr | ||||
9. | ALA5093991 | 31b | t1/2 | = | 0.59 | hr | ALA5030372 | hr | ||||
10. | ALA5093991 | 31b | IC50 | = | 0.17 | nM | ALA5030371 | 9.77 | nM | |||
11. | ALA5093991 | 31b | IC50 | = | 1.6 | nM | ALA5030370 | 8.80 | nM | Homo sapiens |