Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Assay Description	Comment	Assay	Assay Organism
1.	PF-06952229	PF-06952229	INH	=	94	%	ALA5224857			%	Homo sapiens
2.	PF-06952229	PF-06952229	IC50	=	0.024	uM	ALA5224856	7.62		nM	Homo sapiens
3.	PF-06952229	PF-06952229	IC50	=	7.29	uM	ALA5224855	5.14		nM	Homo sapiens
4.	PF-06952229	PF-06952229	Stability	=	87	%	ALA5224854			%
5.	PF-06952229	PF-06952229	Stability	=	55	%	ALA5224853			%
6.	PF-06952229	PF-06952229	IC50	>	1000	uM	ALA5224852			nM	Homo sapiens
7.	PF-06952229	PF-06952229	IC50	=	0.057	uM	ALA5224851	7.24		nM	Homo sapiens
8.	PF-06952229	PF-06952229	IC50	>	1000	uM	ALA5224850			nM	Homo sapiens
9.	PF-06952229	PF-06952229	IC50	>	1000	uM	ALA5224849			nM	Homo sapiens
10.	PF-06952229	PF-06952229	Cmax	=	7.07	uM	ALA5224848			nM
11.	PF-06952229	PF-06952229	CL	=	1.1	L/hr/kg	ALA5224847			mL.min-1.kg-1
12.	PF-06952229	PF-06952229	AUC	=	16.2	uM.hr	ALA5224846		standard_value was converted from uM.hr to ng.hr.mL-1 using the parent compound MW	ng.hr.mL-1
13.	PF-06952229	PF-06952229	F	=	87	%	ALA5224845			%
14.	PF-06952229	PF-06952229	beta t1/2	=	2.09	hr	ALA5224844			hr
15.	PF-06952229	PF-06952229	INH	>	50	%	ALA5224843			%	Homo sapiens
16.	PF-06952229	PF-06952229	INH	>	50	%	ALA5224842			%	Homo sapiens
17.	PF-06952229	PF-06952229	Activity	=	106	%	ALA5149932			%	Mus musculus
18.	PF-06952229	PF-06952229	Time	=	59	day	ALA5149931			hr	Mus musculus
19.	PF-06952229	PF-06952229	Activity	=	18	%	ALA5149930			%	Mus musculus
20.	PF-06952229	PF-06952229	Time	=	33.8	day	ALA5149929			hr	Mus musculus