| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  EZM0414 | EZM-0414 | F | = | 97 | % | ALA5125593 | % | ||||
| 2. | EZM0414 | EZM-0414 | t1/2 | = | 3.8 | hr | ALA5125592 | hr | ||||
| 3. | EZM0414 | EZM-0414 | AUC | = | 10.5 | ug.hr/ml | ALA5125591 | ng.hr.mL-1 | ||||
| 4. | EZM0414 | EZM-0414 | Cmax | = | 2.1 | ug ml-1 | ALA5125590 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 5. | EZM0414 | EZM-0414 | t1/2 | = | 4 | hr | ALA5125585 | hr | ||||
| 6. | EZM0414 | EZM-0414 | AUC | = | 2.1 | ug.hr/ml | ALA5125584 | ng.hr.mL-1 | ||||
| 7. | EZM0414 | EZM-0414 | Vdss | = | 4.1 | L/Kg | ALA5125583 | L.kg-1 | ||||
| 8. | EZM0414 | EZM-0414 | CL | = | 16.2 | ml/min.kg | ALA5125582 | mL.min-1.kg-1 | ||||
| 9. | EZM0414 | EZM-0414 | F | > | 100 | % | ALA5125581 | % | ||||
| 10. | EZM0414 | EZM-0414 | t1/2 | = | 1.8 | hr | ALA5125580 | hr | ||||
| 11. | EZM0414 | EZM-0414 | AUC | = | 27 | ug.hr/ml | ALA5125579 | ng.hr.mL-1 | ||||
| 12. | EZM0414 | EZM-0414 | Cmax | = | 8.6 | ug ml-1 | ALA5125578 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 13. | EZM0414 | EZM-0414 | t1/2 | = | 1.8 | hr | ALA5125573 | hr | ||||
| 14. | EZM0414 | EZM-0414 | AUC | = | 0.8 | ug.hr/ml | ALA5125572 | ng.hr.mL-1 | ||||
| 15. | EZM0414 | EZM-0414 | Vdss | = | 4.7 | L/Kg | ALA5125571 | L.kg-1 | ||||
| 16. | EZM0414 | EZM-0414 | CL | = | 43 | ml/min.kg | ALA5125570 | mL.min-1.kg-1 | ||||
| 17. | EZM0414 | EZM-0414 | INH | = | 93 | % | ALA5125569 | % | ||||
| 18. | EZM0414 | EZM-0414 | INH | = | 90 | % | ALA5125568 | % | ||||
| 19. | EZM0414 | EZM-0414 | AUC | = | 21.4 | ug.hr/ml | ALA5125567 | ng.hr.mL-1 | ||||
| 20. | EZM0414 | EZM-0414 | AUC | = | 9.4 | ug.hr/ml | ALA5125566 | ng.hr.mL-1 |
The page will load shortly, Thanks for your patience!