Activities

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Activities

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#	Name	Compound Key	Action Type	Relation	Activity Value	Units	Assay ID	Comment	Assay	Assay Organism
1.	ALA5170381	9n	Fu	=	40.1	%	ALA5250297
2.	ALA5170381	9n	K(p,uu,brain)	=	6.44		ALA5250296
3.	ALA5170381	9n	K(p,uu,brain)	=	1.59		ALA5250295
4.	ALA5170381	9n	Kp	=	6.44		ALA5250294
5.	ALA5170381	9n	Kp	=	2.78		ALA5250293
6.	ALA5170381	9n	AUC	=	4561	hr.ng/ml	ALA5250292		ng.hr.mL-1
7.	ALA5170381	9n	AUC	=	952	hr.ng/ml	ALA5250291		ng.hr.mL-1
8.	ALA5170381	9n	Cmax	=	860	ng/ml	ALA5250290	standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
9.	ALA5170381	9n	Cmax	=	527	ng/ml	ALA5250289	standard_value was converted from ug.mL-1 to nM using the parent compound MW	nM
10.	ALA5170381	9n	Tmax	=	0.56	hr	ALA5250288		hr
11.	ALA5170381	9n	Tmax	=	0.28	hr	ALA5250287		hr
12.	ALA5170381	9n	MRT	=	8.43	hr	ALA5250286		hr
13.	ALA5170381	9n	MRT	=	2.12	hr	ALA5250285		hr
14.	ALA5170381	9n	t1/2	=	9.11	hr	ALA5250284		hr
15.	ALA5170381	9n	t1/2	=	2.14	hr	ALA5250283		hr
16.	ALA5170381	9n	Ki	>	10000	nM	ALA5250282		nM	Homo sapiens
17.	ALA5170381	9n	Fu	=	22.9	%	ALA5250281
18.	ALA5170381	9n	CLH	=	93.9	ml/min.kg	ALA5250280		mL.min-1.kg-1
19.	ALA5170381	9n	CLH	<	20	ml/min.kg	ALA5250279		mL.min-1.kg-1
20.	ALA5170381	9n	Ki	>	10000	nM	ALA5250278		nM	Homo sapiens