# | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1. | ALA5170470 | Verinurad | IC50 | = | 4.21 | uM | ALA5157470 | 5.38 | nM | |||
2. | ALA5170470 | Verinurad | IC50 | = | 2.14 | uM | ALA5157469 | 5.67 | nM | |||
3. | ALA5170470 | Verinurad | IC50 | = | 0.24 | uM | ALA5157468 | 6.62 | nM | |||
4. | ALA5170470 | Verinurad | IC50 | = | 5.01 | uM | ALA5157467 | 5.30 | nM | |||
5. | ALA5170470 | Verinurad | IC50 | = | 1.24 | uM | ALA5157466 | 5.91 | nM | |||
6. | ALA5170470 | Verinurad | IC50 | = | 0.11 | uM | ALA5157465 | 6.96 | nM | |||
7. | ALA5170470 | Verinurad | IC50 | = | 108.78 | uM | ALA5157461 | nM | Homo sapiens | |||
8. | ALA5170470 | Verinurad | IC50 | = | 197.45 | uM | ALA5157460 | nM | Homo sapiens | |||
9. | ALA5170470 | Verinurad | F | = | 21.47 | % | ALA5157459 | % | ||||
10. | ALA5170470 | Verinurad | MRT | = | 3.46 | hr | ALA5157458 | hr | ||||
11. | ALA5170470 | Verinurad | MRT | = | 4.05 | hr | ALA5157457 | hr | ||||
12. | ALA5170470 | Verinurad | AUC | = | 19657.48 | ng/mL.hr | ALA5157456 | ng.hr.mL-1 | ||||
13. | ALA5170470 | Verinurad | AUC | = | 4128.91 | ng/mL.hr | ALA5157455 | ng.hr.mL-1 | ||||
14. | ALA5170470 | Verinurad | t1/2 | = | 3.49 | hr | ALA5157454 | hr | ||||
15. | ALA5170470 | Verinurad | t1/2 | = | 4.01 | hr | ALA5157453 | hr | ||||
16. | ALA5170470 | Verinurad | Cmax | = | 7214.58 | ng/ml | ALA5157452 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
17. | ALA5170470 | Verinurad | Tmax | = | 0.09 | hr | ALA5157451 | hr | ||||
18. | ALA5170470 | Verinurad | Activity | = | 2371.02 | uM | ALA5157450 | uM | Mus musculus | |||
19. | ALA5170470 | Verinurad | IC50 | = | 18.75 | uM | ALA5157449 | 4.73 | nM | Homo sapiens | ||
20. | ALA5170470 | Verinurad | Tmax | = | 0.46 | hr | ALA5157448 | hr |