| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5170489 | 18 | IC50 | = | 4.8 | uM | ALA5142894 | 5.32 | nM | Mus musculus | ||
| 2. | ALA5170489 | 18 | IC50 | > | 30 | uM | ALA5142893 | nM | Homo sapiens | |||
| 3. | ALA5170489 | 18 | IC50 | = | 10 | uM | ALA5142892 | 5.00 | nM | Homo sapiens | ||
| 4. | ALA5170489 | 18 | IC50 | = | 6.8 | uM | ALA5142891 | 5.17 | nM | |||
| 5. | ALA5170489 | 18 | IC50 | > | 30 | uM | ALA5142890 | nM | Homo sapiens | |||
| 6. | ALA5170489 | 18 | IC50 | = | 2.6 | uM | ALA5142889 | 5.58 | nM | Homo sapiens | ||
| 7. | ALA5170489 | 18 | INH | > | 50 | % | ALA5142888 | % | Homo sapiens | |||
| 8. | ALA5170489 | 18 | INH | > | 50 | % | ALA5142887 | % | Homo sapiens | |||
| 9. | ALA5170489 | 18 | pKa | = | 7.3 | ALA5142886 | ||||||
| 10. | ALA5170489 | 18 | t1/2 | = | 6.2 | hr | ALA5142885 | hr | ||||
| 11. | ALA5170489 | 18 | Vdss | = | 5.4 | L/Kg | ALA5142884 | L.kg-1 | ||||
| 12. | ALA5170489 | 18 | CL | = | 16 | ml/min.kg | ALA5142883 | mL.min-1.kg-1 | ||||
| 13. | ALA5170489 | 18 | F | = | 52 | % | ALA5142882 | % | ||||
| 14. | ALA5170489 | 18 | t1/2 | = | 3.7 | hr | ALA5142881 | hr | ||||
| 15. | ALA5170489 | 18 | Vdss | = | 2.1 | L/Kg | ALA5142880 | L.kg-1 | ||||
| 16. | ALA5170489 | 18 | CL | = | 18 | ml/min.kg | ALA5142879 | mL.min-1.kg-1 | ||||
| 17. | ALA5170489 | 18 | F | = | 58 | % | ALA5142878 | % | ||||
| 18. | ALA5170489 | 18 | CLH | < | 1 | uL/min | ALA5142877 | uL/min | ||||
| 19. | ALA5170489 | 18 | CLH | = | 4.4 | uL/min | ALA5142876 | uL/min | ||||
| 20. | ALA5170489 | 18 | CLH | = | 0.6 | uL/min | ALA5142875 | uL/min |
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