| # | Name | Compound Key | Action Type | Relation | Activity Value | Units | Assay ID | Assay Description | Comment | Assay | Assay Organism | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1. |  ALA5172782 | I-24 | Activity | 0 | ALA5129606 | Non-Toxic | ||||||
| 2. | ALA5172782 | I-24 | TGI | = | 93.5 | % | ALA5129605 | % | Homo sapiens | |||
| 3. | ALA5172782 | I-24 | Activity | 0 | ALA5129604 | Active | Homo sapiens | |||||
| 4. | ALA5172782 | I-24 | Activity | 0 | ALA5129603 | Active | Homo sapiens | |||||
| 5. | ALA5172782 | I-24 | Vdss | = | 7.9 | L/Kg | ALA5129602 | L.kg-1 | ||||
| 6. | ALA5172782 | I-24 | MRT | = | 3.5 | hr | ALA5129601 | hr | ||||
| 7. | ALA5172782 | I-24 | MRT | = | 6.6 | hr | ALA5129600 | hr | ||||
| 8. | ALA5172782 | I-24 | CL | = | 36.2 | ml/min.kg | ALA5129599 | mL.min-1.kg-1 | ||||
| 9. | ALA5172782 | I-24 | AUC | = | 921.8 | ng.hr/ml | ALA5129598 | ng.hr.mL-1 | ||||
| 10. | ALA5172782 | I-24 | AUC | = | 1762.5 | ng.hr/ml | ALA5129597 | ng.hr.mL-1 | ||||
| 11. | ALA5172782 | I-24 | AUCt | = | 878.8 | ng.hr/ml | ALA5129596 | ng.hr.mL-1 | ||||
| 12. | ALA5172782 | I-24 | AUCt | = | 1720.5 | ng.hr/ml | ALA5129595 | ng.hr.mL-1 | ||||
| 13. | ALA5172782 | I-24 | Cmax | = | 345.7 | ng/ml | ALA5129594 | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | standard_value was converted from ug.mL-1 to nM using the parent compound MW | nM | |||
| 14. | ALA5172782 | I-24 | t1/2 | = | 2.5 | hr | ALA5129593 | hr | ||||
| 15. | ALA5172782 | I-24 | t1/2 | = | 4.1 | hr | ALA5129592 | hr | ||||
| 16. | ALA5172782 | I-24 | Activity | = | 12.18 | % | ALA5129591 | % | Homo sapiens | |||
| 17. | ALA5172782 | I-24 | Activity | = | 29.32 | % | ALA5129590 | % | Homo sapiens | |||
| 18. | ALA5172782 | I-24 | Activity | = | 58.51 | % | ALA5129589 | % | Homo sapiens | |||
| 19. | ALA5172782 | I-24 | Activity | = | 13.28 | % | ALA5129588 | % | Homo sapiens | |||
| 20. | ALA5172782 | I-24 | Activity | = | 32.28 | % | ALA5129587 | % | Homo sapiens |
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